"Pre-existing renal function impairment due to acute kidney injury or chronic kidney disease is the only independent patient-related risk factor of CI-AKI 8,10. In the setting of chronic kidney disease, the estimated glomerular filtration rate (eGFR) should be used to stratify the CI-AKI risk. Patients with eGFR > 30 mL/min/1.73 m2 are considered not to be at risk of CI-AKI after intravenous (IV) administration of contrast media 8-10. For intra-arterial administration with renal first pass a higher threshold of 45 mL/min/1.73 m2 is considered safe by the European Society of Urogenital Radiology 10."
Expected headings
"Pre-existing renal function impairment"
"Other patient related factors"
"Contrast administration related factors"
"Prophylaxis"
"Intravenous hydration"
"Other prophylactic practices"
"Choice of contrast medium"
"Prognosis"
"There is no accepted pathophysiological explanation of CI-AKI 8,11. Fluctuations in the renal function (measured by the serum creatinine) are more common and pronounced in patients with pre-existing renal impairment, regardless of whether they receive iodinated contrast media or not. Therefore, many cases of CI-AKI might have been erroneously attributed to such fluctuations stemming from an underlying condition rather than from the contrast media application 1,11."
"There is no evidence that contrast media administration is associated with relevant outcomes such as the need for dialysis or death 1,2,7,11."