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Lint: cutaneous-squamous-cell-carcinoma

Headings Spacing
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"Ultrasound "

Line 43:1 · Never put spaces at either end of headings.

"MRI "

Line 61:1 · Never put spaces at either end of headings.
En Dash
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"excise low-risk tumours with 46 mm margins; use Mohs surgery for high-risk areas (face, ears) or recurrent tumours 9"

Line 85:38 · Use a hyphen-minus ('-') instead of an en-dash ('–').
Eponym Apostrophe
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"Histologically, it is characterised by nests, sheets, or cords of atypical squamous cells invading the dermis. Tumour cells exhibit eosinophilic cytoplasm, enlarged hyperchromatic nuclei, and intercellular bridges. Keratin pearls and individual cell keratinisation are hallmark features 4. Poorly differentiated cSCC shows minimal keratinisation and marked nuclear pleomorphism. The tumour often originates in sun-damaged skin, evidenced by adjacent solar elastosis. Actinic keratosis or Bowen's disease may be present as precursor lesions 4,5. Perineural invasion, when present, indicates aggressive behaviour. Tumour depth (>6 mm) and poor differentiation are important prognostic factors 6."

Line 35:503 · Radiopaedia prefers the non-possessive eponym: 'Bowen's disease'.
Colons
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"positive: CK5/6, p40, p63 (squamous differentiation markers)"

Line 38:16 · The first word after a colon should almost always be lowercase. In this case, it's not: ': CK5/6, p40'.

"negative: BerEP4 (helps distinguish from basal cell carcinoma)"

Line 39:16 · The first word after a colon should almost always be lowercase. In this case, it's not: ': BerEP4 (helps'.
Acronyms
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"p16: often lost in UV-related cSCC (unlike Human Papillomavirus (HPV)-positive head and neck SCC)"

Line 40:27 · 'UV' has no definition. Spell it out if it's unfamiliar to the audience.

"p16: often lost in UV-related cSCC (unlike Human Papillomavirus (HPV)-positive head and neck SCC)"

Line 40:101 · 'SCC' has no definition. Spell it out if it's unfamiliar to the audience.

"start immunotherapy (cemiplimab/pembrolizumab) for metastatic/unresectable cSCC; reserve chemotherapy (cisplatin/5-FU) for refractory cases"

Line 87:130 · 'FU' has no definition. Spell it out if it's unfamiliar to the audience.
List Caps
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"High-risk features:"

Line 68:4 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Radiologic features"

Line 42:1 · "Radiologic features" is not a recognised heading for this article type.

"Ultrasound "

Line 43:1 · "Ultrasound " is not a recognised heading for this article type.

"CT"

Line 48:1 · "CT" is under the wrong parent heading (found under "Radiologic features").

"MRI "

Line 61:1 · "MRI " is not a recognised heading for this article type.

"PET-CT"

Line 75:1 · "PET-CT" should be H3, not H2.
Oxford Comma
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"gold standard: skin biopsy (shave, punch or excisional) with histopathology 3"

Line 6:36 · Use the Oxford comma in 'shave, punch or excisional'.

"advanced/locally invasive: loss of normal tissue planes, possible perineural, cartilage or bone involvement"

Line 46:74 · Use the Oxford comma in 'perineural, cartilage or bone'.
Inline EG
suggestion

"perineural spread: nerve thickening and enhancement (e.g. facial nerve branches)"

Line 70:60 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.

"immunosuppression (e.g. transplant patients)"

Line 99:33 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.

"survival rates are generally lower for immunosuppressed patients (e.g. transplant recipients)"

Line 112:73 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.
Semicolons
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"excise low-risk tumours with 4–6 mm margins; use Mohs surgery for high-risk areas (face, ears) or recurrent tumours 9"

Line 85:51 · Use semicolons judiciously.

"start immunotherapy (cemiplimab/pembrolizumab) for metastatic/unresectable cSCC; reserve chemotherapy (cisplatin/5-FU) for refractory cases"

Line 87:94 · Use semicolons judiciously.

"melanoma: more likely to metastasise; may have similar nodal involvement"

Line 105:51 · Use semicolons judiciously.