"The initial clinical staging of the primary malignant melanoma is essential and incorporates clinical and/or radiological evaluation for metastatic disease. The Breslow thickness and Clarke level of cutaneous melanoma classification has been widely discussed, as has the AJCC TNM staging protocol."
"Metastatic melanoma remains the third most common cause of intracranial metastases, behind both lung and breast cancer 3. Metastasis to the CNS are designated M1d disease as per the 8th edition AJCC melanoma staging system."
"T1: typically hyperintense due to a reduction in T1 relaxation time associated with the presence of melanin"
"T2: reduced T2 signal"
"T1 C+ (Gd): demonstrates peripheral rim enhancement with a heterogeneous pattern of enhancement 3"
"T1:"
"The initial clinical staging of the primary malignant melanoma is essential and incorporates clinical and/or radiological evaluation for metastatic disease. The Breslow thickness and Clarke level of cutaneous melanoma classification has been widely discussed, as has the AJCC TNM staging protocol."
"The initial clinical staging of the primary malignant melanoma is essential and incorporates clinical and/or radiological evaluation for metastatic disease. The Breslow thickness and Clarke level of cutaneous melanoma classification has been widely discussed, as has the AJCC TNM staging protocol."
"The lungs and pleura are the second most common site of malignant melanoma metastases after lymph node involvement, with 85% of end-stage melanoma patients having evidence of lung metastases at autopsy 4. Metastasis to the lung are designated M1b disease as per the 8th edition AJCC melanoma staging system."
"Metastatic melanoma remains the third most common cause of intracranial metastases, behind both lung and breast cancer 3. Metastasis to the CNS are designated M1d disease as per the 8th edition AJCC melanoma staging system."
"Kaposi sarcoma"
Expected headings
"Nodal metastases"
"Ultrasound"
"CT"
"Thoracic metastases"
"PET-CT"
"CNS and head/neck metastases"
"MRI"
"Abdominal and pelvic metastases"
"CT"
"MRI"
"PET-CT"
"Bone metastases"
"Melanoma accounts for ~5% of all skin cancers, however, it remains the leading cause of death amongst skin cancers. The risk of metastatic progression has a strong association with the site of the initial primary melanoma, with melanomas arising from the head, neck and trunk carrying a higher risk of metastatic progression than those melanomas arising from the limbs 1,2."
"lymph nodes with metastatic disease may have an irregular, hypoechoic or lobulated appearance 3"