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Lint: cystinosis

Strong
warning

"renal manifestations"

Line 8:1 · Generally, don't use bold in text: '<strong>renal manifestations</strong>'

"extra-renal manifestations"

Line 19:1 · Generally, don't use bold in text: '<strong>extra-renal manifestations</strong>'
Prefix Hyphens
warning

"extra-renal manifestations"

Line 19:9 · A prefix takes a hyphen only to avoid a duplicate letter: 'extra-renal'.
There Is
suggestion

"There are three main clinical phenotypes:"

Line 41:4 · Don't start a sentence with 'There are'.