"T2/FLAIR: hyperintense with no perilesional oedema"
"T1 C+ (Gd): poor enhancement 3"
"DWI/ADC: central low ADC values4"
"DWI/ADC: central low ADC values4"
"Diffuse glioneuronal tumour with oligodendroglial features and nuclear clusters occurs mainly in children, although some higher-age cases have been described 1, 3."
"GFAP: negative"
Expected headings
"Location"
"Microscopic appearance"
"Immunophenotype"
"Diffuse glioneuronal tumour with oligodendroglial features and nuclear clusters demonstrates histological, molecular and immunophenotype features reminiscent of a wide spectrum of tumours, such as oligodendroglioma grade 3, neurocytoma, dysembryoplastic neuroepithelial tumour (DNET), primitive neuroectodermal tumours and even glioblastoma 1, 3. Therefore it is likely that in the near future many previously diagnosed high-grade CNS tumours will be re-assigned to this entity based on its specific methylation profile."
"Diffuse glioneuronal tumour with oligodendroglial features and nuclear clusters demonstrates histological, molecular and immunophenotype features reminiscent of a wide spectrum of tumours, such as oligodendroglioma grade 3, neurocytoma, dysembryoplastic neuroepithelial tumour (DNET), primitive neuroectodermal tumours and even glioblastoma 1, 3. Therefore it is likely that in the near future many previously diagnosed high-grade CNS tumours will be re-assigned to this entity based on its specific methylation profile."