Login
Toggle sidebar

Lint: diffuse-midline-glioma-h3-k27-altered

Headings Spacing
error

"Clinical presentation "

Line 4:1 · Never put spaces at either end of headings.
Adjectival Hyphens
error

"Usually, the tumour is homogeneous pre-treatment, however, in a minority of patients areas of necrosis may be present."

Line 42:39 · Only use medical adjectival hyphens where the letters at the end and start of the compound word are the same, e.g. post-transplant. In this case, don't use the hyphen: 'pre-treatment,'.

"enhancement can be seen post-radiotherapy"

Line 60:32 · Only use medical adjectival hyphens where the letters at the end and start of the compound word are the same, e.g. post-transplant. In this case, don't use the hyphen: 'post-radiotherapy'.
Strong List Colon Position
error

"T1: hypointense"

Line 47:8 · When enboldening an intro, the colon should not be bold. '<strong>T1:</strong> hypointense'

"T2: "

Line 49:4 · When enboldening an intro, the colon should not be bold. '<strong>T2:</strong> '

"T1 C+ (Gd): "

Line 56:4 · When enboldening an intro, the colon should not be bold. '<strong>T1 C+ (Gd):</strong> '

"DWI/ADC:"

Line 64:4 · When enboldening an intro, the colon should not be bold. '<strong>DWI/ADC:</strong>'

"T2*/SWI: areas of marked hypointensity/blooming in cases of intralesional haemorrhage 5"

Line 70:8 · When enboldening an intro, the colon should not be bold. '<strong>T2*/SWI:</strong> areas'
EG List And
warning

"Diffuse midline glioma, H3 K27-altered is a specific entity that represents the majority of diffuse intrinsic pontine gliomas, although identical tumours are also found elsewhere in the midline (e.g. brainstem, spinal cord and thalamus) 1. They are aggressive tumours with a poor prognosis and are considered WHO grade 4 tumours regardless of histological features 1,3,4."

Line 1:223 · An e.g. list gives selected examples, so it should not end with 'and' or 'or': 'e.g. brainstem, spinal cord and'.
Acronyms
warning

"GFAP: variable"

Line 31:11 · 'GFAP' has no definition. Spell it out if it's unfamiliar to the audience.

"Importantly, unlike adult diffuse gliomas, mutations of IDH, CDKN2A and/or CDKN2B deletions, TERT promoter mutations, and MGMT promoter methylation are rare in diffuse midline gliomas, H3 K27-altered 4."

Line 35:97 · 'TERT' has no definition. Spell it out if it's unfamiliar to the audience.
List Caps
warning

"NeuN: negative"

Line 33:11 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.
Emphasis
warning

"These mutations are in the histone H3F3A gene (K27M mutations) or less frequently HIST1H3B and HIST2H3C genes 2,3."

Line 38:39 · Italics should be used only in exceptional circumstances: '<em>H3F3A</em> gene (K27M mutations) or less frequently <em>HIST1H3B</em>'
Headings Valid
warning

Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Clinical presentation "

Line 4:1 · "Clinical presentation " is not a recognised heading for this article type.
Oxford Comma
suggestion

"The clinical presentation depends upon the location of the tumour. Typically patients with brainstem tumours present with multiple cranial nerve palsies, depending on the location of the tumour, and signs of raised intracranial pressure. Cerebellar signs may also be elicited including ataxia, dysarthria, nystagmus and sleep apnoea."

Line 5:305 · Use the Oxford comma in 'dysarthria, nystagmus and sleep'.
Commas
suggestion

"Importantly, unlike adult diffuse gliomas, mutations of IDH, CDKN2A and/or CDKN2B deletions, TERT promoter mutations, and MGMT promoter methylation are rare in diffuse midline gliomas, H3 K27-altered 4."

Line 35:15 · More than 5 commas in a single sentence might make it more difficult to read.