"EGFR exon 19 deletion (E19del): considered most common activating mutation in advanced non-small cell lung cancer (NSCLC) 8"
"EGFR exon 21 deletion (E21del): considered next most common activating mutation in advanced non-small cell lung cancer (NSCLC) 9"
"An epidermal growth factor receptor (EGFR) mutation may be expressed in a large proportion of non-small cell lung carcinomas (NSCLC). However, certain subtypes such as invasive mucinous adenocarcinoma of the lung can have very low expression."
"KRAS mutation"
"HER-2 mutations in lung cancer"
"ROS 1 mutation"
Expected headings
"Clinical importance"
"Specific types"
"There is also some (but not 100% 5) mutual exclusivity with ALK gene arrangements."
"Useful for assessing the suitability of certain anticancer drugs (tyrosine kinase inhibitors) that inhibit EGFR such as gefitinib (Iressa), erlotinib (Tarceva), and afatinib (Gilotrif) 7."