Radiopaedia Helpers

Emphasis

warning

"Anaplastic lymphoma kinase (ALK) gene rearrangements are known to occur in association with several tumours. The genes code for an enzyme called anaplastic lymphoma kinase (ALK) or ALK tyrosine kinase receptor (also known as CD246) which is thought to play a role in brain development and exerts its effects on specific neurones in the nervous system. Rearrangements could result in anaplastic lymphoma kinase-1 (ALK-1) protein expression."

Line 1:40 · Italics should be used only in exceptional circumstances: '<em>ALK</em>'

Acronyms

warning

"HER-2 mutations in lung cancer"

Line 33:8 · 'HER' has no definition. Spell it out if it's unfamiliar to the audience.

"KRAS mutation"

Line 34:8 · 'KRAS' has no definition. Spell it out if it's unfamiliar to the audience.

"EGFR mutation"

Line 35:8 · 'EGFR' has no definition. Spell it out if it's unfamiliar to the audience.

Parentheses

suggestion

"Anaplastic lymphoma kinase (ALK) gene rearrangements are known to occur in association with several tumours. The genes code for an enzyme called anaplastic lymphoma kinase (ALK) or ALK tyrosine kinase receptor (also known as CD246) which is thought to play a role in brain development and exerts its effects on specific neurones in the nervous system. Rearrangements could result in anaplastic lymphoma kinase-1 (ALK-1) protein expression."

Line 1:39 · Use parentheses judiciously. There are at least 3 sets in this paragraph.

Inline EG

suggestion

"Useful in determining the suitability of ALK-1 inhibitor therapy (e.g. crizotinib)."

Line 29:69 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.

Lint: anaplastic-lymphoma-kinase-alk-gene-rearrangements