"post-renal transplant 31"
"Xp11.2 translocation: subtype predominantly seen in young patients, comprises a third of paediatric renal cell carcinomas 34"
"Imaging is essential in accurately staging renal cell carcinomas (see renal cell carcinoma staging (TNM) and Robson staging system) and in operative planning."
"On non-contrast CT, lesions are of soft tissue attenuation between 20-70 HU 23,24. Larger lesions frequently have areas of necrosis. Approximately 30% demonstrate some calcification 7."
Expected headings
"Paraneoplastic syndromes"
"Grading"
"FDG-PET"
"von Hippel-Lindau syndrome: greater tendency for bilateral renal cell carcinomas as well as a presentation at a younger age; clear cell subtype"
"Birt-Hogg-Dubé syndrome: often bilateral; chromophobe subtype"
"type II: inherited, bilateral and multifocal"
"Treatment of renal cell carcinomas is usually with radical nephrectomy if feasible. However, in elderly patients or those with co-morbidities, and especially those with smaller tumours suggestive of papillary histology (see MRI findings above), organ-sparing treatment can be entertained. This ranges from adrenal sparing nephrectomy to partial nephrectomy, performed either open or laparoscopically. Additionally, percutaneous radiofrequency, chemical or cryoablation (typically under CT guidance), which can be carried out with only local anaesthetic and sedation, has been introduced in selected cases 11."
"Approximately one-third of newly diagnosed cases of renal cell carcinomas have metastatic disease at the time of initial presentation (synchronous metastases) 30. The most common sites of metastasis are, in order, the lungs, bones, lymph nodes, liver, adrenals, and brain 25."