"Patients may present with numerous other symptoms and signs 2, e.g. palpable mass, flank pain, urinary tract infections, haematuria, renal failure, or hypertension 3."
"Angiomyolipomas are members of the perivascular epithelioid cells tumour group (PEComas) and are composed of variable amounts of three components; blood vessels (-angio) lacking elastic tissue, plump spindle cells (-myo), and adipose tissue (-lipo)."
"Angiomyolipomas are members of the perivascular epithelioid cells tumour group (PEComas) and are composed of variable amounts of three components; blood vessels (-angio) lacking elastic tissue, plump spindle cells (-myo), and adipose tissue (-lipo)."
"mTOR inhibitors (e.g. everolimus) have been shown to significantly decrease AML size in both TSC and sporadic cases, particularly the highly vascularised fat-poor component, with dramatic reduction in the size of the arteries and aneurysms thereby reducing the risk of haemorrhage and renal impairment 30. Side effects can be significant."
Expected headings
"Variants"
"Digital subtraction angiography (DSA)"
"The remaining 20% are associated with phakomatoses, the vast majority in the setting of tuberous sclerosis. Angiomyolipomas are found in 25-50% of tuberous sclerosis patients 23. They have also been described in the setting of von Hippel-Lindau syndrome (vHL) and neurofibromatosis type 1 (NF1) 5,7. In these cases, they present earlier (usually identified by the age of 10 years), are larger, and are far more numerous. They are more likely to be fat-poor, which accounts for their earlier presentation 2,6,7. They have also been associated with lymphangioleiomyomatosis (LAM) 20."
"Angiomyolipomas are members of the perivascular epithelioid cells tumour group (PEComas) and are composed of variable amounts of three components; blood vessels (-angio) lacking elastic tissue, plump spindle cells (-myo), and adipose tissue (-lipo)."
"Patients may present with numerous other symptoms and signs 2, e.g. palpable mass, flank pain, urinary tract infections, haematuria, renal failure, or hypertension 3."
"Angiomyolipomas are members of the perivascular epithelioid cells tumour group (PEComas) and are composed of variable amounts of three components; blood vessels (-angio) lacking elastic tissue, plump spindle cells (-myo), and adipose tissue (-lipo)."
"The cornerstone of diagnosis in all modalities is the demonstration of macroscopic fat; however, in the setting of haemorrhage, or when lesions contain little fat, it may be difficult to distinguish an angiomyolipoma from a renal cell carcinoma."
"presence of a large vessel extending into the renal cortex suggestive of AML; liposarcoma is hypovascular"