Radiopaedia Helpers

neurofibromatosis-type-1

Optional Plurals

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"rarer associations: rhabdomyosarcoma, leiomyoma(s), leiomyosarcoma, ganglioglioma"

Line 56:56 · Do not use plurals in parentheses such as in 'leiomyoma(s)'.

Acronyms

warning

"≥2 neurofibromas OR ≥1 plexiform neurofibroma"

Line 23:32 · 'OR' has no definition. Spell it out if it's unfamiliar to the audience.

"≥2 Lisch nodules OR ≥2 choroidal abnormalities"

Line 25:25 · 'OR' has no definition. Spell it out if it's unfamiliar to the audience.

"A mnemonic to help remember these diagnostic clinical features is CAFE SPOT."

Line 30:78 · 'SPOT' has no definition. Spell it out if it's unfamiliar to the audience.

Emphasis

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"a heterozygous pathogenic NF1 variant with a variant allele fraction of 50% in apparently normal tissue such as white blood cells"

Line 27:34 · Italics should be used only in exceptional circumstances: '<em>NF1</em>'

Headings Valid

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Expected headings

H1 Terminology
H1 Usage
H1 Epidemiology
H2 Risk factors
H2 Associations
H1 Clinical presentation
H2 Complications
H1 Diagnosis
H2 Diagnostic criteria
H2 Diagnostic clues
H1 Pathology
H2 Aetiology
H2 Location
H2 Classification
H2 Macroscopic appearance
H2 Microscopic appearance
H2 Immunophenotype
H2 Markers
H2 Genetics
H1 Radiographic features
H2 Plain radiograph
H2 Mammography
H2 Antenatal ultrasound
H2 Transoesophageal echocardiography
H2 Ultrasound
H2 CT
H3 Dual-energy CT
H2 Angiography (DSA)
H2 MRI
H2 CT/MRI
H2 Nuclear medicine
H3 PET-CT
H3 PET-MRI
H1 Radiology report
H1 Treatment and prognosis
H2 Complications
H1 History and etymology
H1 Differential diagnosis
H2 Clinical differential diagnosis
H1 Practical points
H1 See also

"Breast"

Line 68:1 · "Breast" is not a recognised heading for this article type.

"Central nervous system"

Line 70:1 · "Central nervous system" is not a recognised heading for this article type.

"Cutaneous"

Line 83:1 · "Cutaneous" is not a recognised heading for this article type.

"Skeletal"

Line 87:1 · "Skeletal" is not a recognised heading for this article type.

"Thoracic"

Line 103:1 · "Thoracic" is not a recognised heading for this article type.

"Vascular"

Line 124:1 · "Vascular" is not a recognised heading for this article type.

There Is

suggestion

"Neurofibromatosis affects 1:2500-3000 individuals ³. In half of the cases, the disease is inherited as an autosomal dominant condition. In the other half, the disease is due to a de novo mutation ⁶. There is a variable expression but 100% penetrance by 5 years of age ⁶."

Line 16:225 · Don't start a sentence with 'There is'.

Semicolons

suggestion

"The NF1 gene locus is on chromosome 17q11.2 and the gene product is neurofibromin, which acts as a tumour suppressor of the Ras/MAPK pathway; inactivation of the gene thus predisposes to tumour development ^6,12,13. For this reason, the disorder is classified as a RASopathy ¹²."

Line 59:160 · Use semicolons judiciously.

"plexiform neurofibroma: considered pathognomonic if present; they may be seen in virtually any location but usually occur in the neck, pelvis, and extremities"

Line 64:74 · Use semicolons judiciously.

Biographical Lifespan

suggestion

"History and etymology"

Line 134:1 · A bold element in the History and etymology section should be a person; it would be useful to have their lifespan details: '<h4>History and etymology</h4> <p>The first name of this condition was von Recklinghausen disease because in 1882, <strong>Friedrich</strong> '

Links

phakomatoses-1