Radiopaedia Helpers

Strong List Colon Position

error

"in/out-of-phase: no signal loss on out-of-phase imaging (phaeochromocytomas rarely contain a significant amount of intracellular lipid) ¹²"

Line 88:8 · When enboldening an intro, the colon should not be bold. 'in/out-of-phase: no'

Isotope Notation

error

"Octreotide is usually labelled with either ¹¹¹In-DTPA (Octreoscan) or (less commonly) ¹²³I-Tyr3-DTPA ⁵."

Line 101:52 · Write the isotope as symbol-mass, e.g. F-18, not '111In'.

"Octreotide is usually labelled with either ¹¹¹In-DTPA (Octreoscan) or (less commonly) ¹²³I-Tyr3-DTPA ⁵."

Line 101:113 · Write the isotope as symbol-mass, e.g. F-18, not '123I'.

"18F-DOPA PET is thought to be highly sensitive according to initial results ³. Gallium-68 DOTATATE PET-CT imaging has also been advocated due to their higher lesion to background tissue contrast and high specificity for phaeochromocytoma ¹⁴."

Line 105:4 · Write the isotope as symbol-mass, e.g. F-18, not '18F'.

"18F-FDOPA (6-[18F]-L-fluoro-L-3, 4-dihydroxyphenylalanine)-based PET-CT imaging can also be a useful tool in diagnosis ¹⁷."

Line 106:4 · Write the isotope as symbol-mass, e.g. F-18, not '18F'.

"18F-FDOPA (6-[18F]-L-fluoro-L-3, 4-dihydroxyphenylalanine)-based PET-CT imaging can also be a useful tool in diagnosis ¹⁷."

Line 106:18 · Write the isotope as symbol-mass, e.g. F-18, not '18F'.

En Dash

error

"These tumours were first described as chromaffin tumours by German pathologist Max Schottelius (1849–1919) in 1886 with the term phaeochromocytoma first used by another German pathologist Ludwig Pick (1868–1944) in 1912 ^23,24. Phaeochromocytoma is a borrowed word from German phäochromocytom ²⁵."

Line 112:121 · Use a hyphen-minus ('-') instead of an en-dash ('–').

"These tumours were first described as chromaffin tumours by German pathologist Max Schottelius (1849–1919) in 1886 with the term phaeochromocytoma first used by another German pathologist Ludwig Pick (1868–1944) in 1912 ^23,24. Phaeochromocytoma is a borrowed word from German phäochromocytom ²⁵."

Line 112:243 · Use a hyphen-minus ('-') instead of an en-dash ('–').

Strong

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"~10% are not associated with hypertension"

Line 8:9 · Generally, don't use bold in text: '10% are not associated with hypertension'

List Caps

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"Carney triad: for extra-adrenal phaeochromocytoma"

Line 27:11 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

Acronyms

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"succinate dehydrogenase subunit B (SDHB) gene mutation"

Line 41:42 · 'SDHB' has no definition. Spell it out if it's unfamiliar to the audience.

"is considered one of the major genes predisposing to paraganglioma/phaeochromocytoma (PPGL) ²⁶"

Line 43:94 · 'PPGL' has no definition. Spell it out if it's unfamiliar to the audience.

"Phaeochromocytomas are a type of paraganglioma. They are catecholamine-secreting tumours derived from chromaffin cells. They typically demonstrate a nesting (Zellballen) pattern on microscopy. This pattern is composed of well-defined clusters of tumour cells containing eosinophilic cytoplasm separated by a fibrovascular stroma. Various pathological scoring systems are in use (PASS, GAPP) to predict differentiation and the likelihood of metastasis ¹⁵."

Line 48:390 · 'PASS' has no definition. Spell it out if it's unfamiliar to the audience.

"Phaeochromocytomas are a type of paraganglioma. They are catecholamine-secreting tumours derived from chromaffin cells. They typically demonstrate a nesting (Zellballen) pattern on microscopy. This pattern is composed of well-defined clusters of tumour cells containing eosinophilic cytoplasm separated by a fibrovascular stroma. Various pathological scoring systems are in use (PASS, GAPP) to predict differentiation and the likelihood of metastasis ¹⁵."

Line 48:396 · 'GAPP' has no definition. Spell it out if it's unfamiliar to the audience.

"18F-FDOPA (6-[18F]-L-fluoro-L-3, 4-dihydroxyphenylalanine)-based PET-CT imaging can also be a useful tool in diagnosis ¹⁷."

Line 106:8 · 'FDOPA' has no definition. Spell it out if it's unfamiliar to the audience.

Litotes

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"~1/3 do not have marked T2 hyperintensity ¹⁸"

Line 84:16 · Consider using 'lack(s)' instead of 'not have'

Emphasis

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"These tumours were first described as chromaffin tumours by German pathologist Max Schottelius (1849–1919) in 1886 with the term phaeochromocytoma first used by another German pathologist Ludwig Pick (1868–1944) in 1912 ^23,24. Phaeochromocytoma is a borrowed word from German phäochromocytom ²⁵."

Line 112:325 · Italics should be used only in exceptional circumstances: 'phäochromocytom'

Headings Valid

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Expected headings

H1 Terminology
H1 Usage
H1 Epidemiology
H2 Risk factors
H2 Associations
H1 Clinical presentation
H2 Complications
H1 Diagnosis
H2 Diagnostic criteria
H2 Diagnostic clues
H1 Pathology
H2 Aetiology
H2 Location
H2 Classification
H2 Macroscopic appearance
H2 Microscopic appearance
H2 Immunophenotype
H2 Markers
H2 Genetics
H1 Radiographic features
H2 Plain radiograph
H2 Mammography
H2 Antenatal ultrasound
H2 Transoesophageal echocardiography
H2 Ultrasound
H2 CT
H3 Dual-energy CT
H2 Angiography (DSA)
H2 MRI
H2 CT/MRI
H2 Nuclear medicine
H3 PET-CT
H3 PET-MRI
H1 Radiology report
H1 Treatment and prognosis
H2 Complications
H1 History and etymology
H1 Differential diagnosis
H2 Clinical differential diagnosis
H1 Practical points
H1 See also

"Genetics"

Line 39:1 · "Genetics" should be H2, not H3.

"Octreotide (somatostatin) scans"

Line 99:1 · "Octreotide (somatostatin) scans" is not a recognised heading for this article type.

"I-123 MIBG (metaiodobenzylguanidine)"

Line 102:1 · "I-123 MIBG (metaiodobenzylguanidine)" is not a recognised heading for this article type.

"PET"

Line 104:1 · "PET" is not a recognised heading for this article type.

Semicolons

suggestion

"110-120 HU of enhancement on the arterial phase suggests phaeochromocytoma, but is not specific; hypervascular metastases could be considered in an appropriate setting"

Line 64:103 · Use semicolons judiciously.

Commas

suggestion

"Over 70% of tumours express somatostatin receptors. Imaging is obtained 4 hours (+/- 24/48 hours) after an intravenous infusion. Unfortunately, the kidney also has somatostatin receptors, as do areas of inflammation, mammary glands, liver, spleen, bowel, gallbladder, thyroid gland, and salivary glands. As such, interpretation can be difficult ⁵."

Line 100:146 · More than 5 commas in a single sentence might make it more difficult to read.

Lint: phaeochromocytoma-1