"Gallium67 scintigraphy may show higher uptake than that of a neurofibroma 6,7."
"Most MPNSTs demonstrate inactivation of a number of genes: NF1, CDKN2A, and PRC2 8."
"EGFR: positive in ~35%"
"It is worth noting that this grading is in contrast many benign neurogenic tumours (e.g. neurofibromas, schwannomas and perineuiomas) that sometimes can give rise to MPNST are given a grade of 1 in the WHO classification of CNS tumours 8."
Expected headings
"Variants"
"Grading"
"Malignant peripheral nerve sheath tumours are estimated to account for 3-5% of all soft-tissue sarcomas 9. They typically present in young and middle-aged adults (20-50 years) 8,9. There is no recognised gender predilection."