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Lint: high-grade-astrocytoma-with-piloid-features-1

Acronyms
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"BRAF"

Line 15:11 · 'BRAF' has no definition. Spell it out if it's unfamiliar to the audience.

"ATRX (mutations or loss)"

Line 18:11 · 'ATRX' has no definition. Spell it out if it's unfamiliar to the audience.
Heterogeneous Spelling
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"HGAP have heterogenous imaging features, difficult to distinguish from glioblastoma or diffuse midline glioma 4."

Line 22:14 · Radiopaedia advises the '-eous' form: 'heterogeneous' rather than 'heterogenous'.
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Molecular characteristics"

Line 11:1 · "Molecular characteristics" is not a recognised heading for this article type.
Semicolons
suggestion

"Due to the small number of patients reported, it is difficult to make strong pronouncements on the epidemiology of this tumour; however, cases so far appear to be primarily in middle-aged and elderly individuals 1,3,4. Neurofibromatosis type 1 appears to be a fairly strong association 1,4."

Line 3:130 · Use semicolons judiciously.
Oxford Comma
suggestion

"Due to the small number of cases reported to date, specific or even suggestive imaging features are not yet evident especially as the tumours that have been described are heterogeneous in location (see above) and appearance 1,4."

Line 24:49 · Use the Oxford comma in 'date, specific or even'.

"Generally, they appear to be heterogeneously/peripherally enhancing lesions with low T1 and high T2/FLAIR signal but usually without diffusion restriction of either central or peripheral components 1,4. Cystic areas, necrosis and elevated perfusion have been reported 4."

Line 25:225 · Use the Oxford comma in 'areas, necrosis and elevated'.
There Is
suggestion

"No tumour specific treatments are available at this time with treatment being empirical consisting of maximal safe surgical resection with concurrent chemoradiotherapy (e.g. temozolomide) 1. There is a suggestion that NF1-associated HGAP may respond mTOR and MAPK inhibitors 4."

Line 29:213 · Don't start a sentence with 'There is'.