"Pre-capillary pulmonary hypertension is considered if the pulmonary artery wedge pressure (PAWP) is ≤15 mmHg, pulmonary vascular resistance (PVR) is ≥3 Wood units (WU), and mPAP is >20 mmHg 29."
"Post-capillary pulmonary hypertension is now defined as mPAP >20 mmHg and PAWP >15 mmHg 29. If the PVR is 3 WU, this is classified as isolated post-capillary pulmonary hypertension, and if the PVR is ≥3 WU, this is classified as combined pre- and post-capillary pulmonary hypertension 29."
"Post-capillary pulmonary hypertension is now defined as mPAP >20 mmHg and PAWP >15 mmHg 29. If the PVR is 3 WU, this is classified as isolated post-capillary pulmonary hypertension, and if the PVR is ≥3 WU, this is classified as combined pre- and post-capillary pulmonary hypertension 29."
"Post-capillary pulmonary hypertension is now defined as mPAP >20 mmHg and PAWP >15 mmHg 29. If the PVR is 3 WU, this is classified as isolated post-capillary pulmonary hypertension, and if the PVR is ≥3 WU, this is classified as combined pre- and post-capillary pulmonary hypertension 29."
"Post-capillary pulmonary hypertension is now defined as mPAP >20 mmHg and PAWP >15 mmHg 29. If the PVR is 3 WU, this is classified as isolated post-capillary pulmonary hypertension, and if the PVR is ≥3 WU, this is classified as combined pre- and post-capillary pulmonary hypertension 29."
"By the time the diagnosis of pulmonary arterial hypertension is made, 90% of patients have an abnormal chest radiograph 3, although sensitivity and specificity are low 12. Features include 11,29:"
"right ventricular dilatation (a right ventricle–to–left ventricle diameter ratio of more than 1:1 at the midventricular level on axial images)"
"right ventricular dilatation (a right ventricle–to–left ventricle diameter ratio of more than 1:1 at the midventricular level on axial images)"
"The use of the term pulmonary arterial hypertension is restricted to those with a haemodynamic profile in which high pulmonary pressure results from elevated precapillary pulmonary resistance and normal pulmonary venous pressure, measured as a pulmonary wedge pressure of ≤15 mmHg. This corresponds to the haemodynamic profiles of groups 1, 3, 4, and 5 in the Dana Point classification system, which was updated during the 5th World Symposium on Pulmonary Hypertension (WSPH)."
"Pre-capillary pulmonary hypertension is considered if the pulmonary artery wedge pressure (PAWP) is ≤15 mmHg, pulmonary vascular resistance (PVR) is ≥3 Wood units (WU), and mPAP is >20 mmHg 29."
"Post-capillary pulmonary hypertension is now defined as mPAP >20 mmHg and PAWP >15 mmHg 29. If the PVR is 3 WU, this is classified as isolated post-capillary pulmonary hypertension, and if the PVR is ≥3 WU, this is classified as combined pre- and post-capillary pulmonary hypertension 29."
"Post-capillary pulmonary hypertension is now defined as mPAP >20 mmHg and PAWP >15 mmHg 29. If the PVR is 3 WU, this is classified as isolated post-capillary pulmonary hypertension, and if the PVR is ≥3 WU, this is classified as combined pre- and post-capillary pulmonary hypertension 29."
"group 5: pulmonary hypertension with unclear and/or multifactorial mechanisms, e.g. haematological disorders; sarcoidosis; pulmonary Langerhans cell histiocytosis; neurofibromatosis type 1; metabolic disorders; chronic renal failure"
"The use of the term pulmonary arterial hypertension is restricted to those with a haemodynamic profile in which high pulmonary pressure results from elevated precapillary pulmonary resistance and normal pulmonary venous pressure, measured as a pulmonary wedge pressure of ≤15 mmHg. This corresponds to the haemodynamic profiles of groups 1, 3, 4, and 5 in the Dana Point classification system, which was updated during the 5th World Symposium on Pulmonary Hypertension (WSPH)."
"At the 6th WSPH, the threshold for diagnosing pulmonary hypertension was lowered to a mean pulmonary arterial pressure (mPAP) >20 mmHg 29. Pressure during exercise is no longer part of the definition."
"The WSPH/WHO classification grouping of pulmonary hypertension 28 is considered the current (c.2024) classification 29. There is a long list of subgroups, but the main entities include 29:"
"Since 1973, the World Symposium on Pulmonary Hypertension (WSPH) has led global efforts on research into pulmonary hypertension, including classification of the condition 29 with several now historical classifications:"
"a right ventricle-to-left ventricle basal diameter ratio exceeding 1.0 (RV/LV ratio >1)"
"The WSPH/WHO classification grouping of pulmonary hypertension 28 is considered the current (c.2024) classification 29. There is a long list of subgroups, but the main entities include 29:"
"The WSPH/WHO classification grouping of pulmonary hypertension 28 is considered the current (c.2024) classification 29. There is a long list of subgroups, but the main entities include 29:"
"group 1: pulmonary arterial hypertension, e.g. idiopathic; heritable; associated with drugs and toxins; associated with connective tissue disease; HIV infection; portal hypertension, etc"
"group 3: pulmonary hypertension associated with lung diseases and/or hypoxia, e.g. COPD and/or emphysema; interstitial lung disease, etc"
Expected headings
"Echocardiography"
"Extracardiac vascular signs"
"Cardiac signs"
"Parenchymal signs"
"Mediastinal signs"
"drugs and toxins, e.g. aminorex (withdrawn from the market), benfluorex, fenfluramine, dexfenfluramine, toxic rapeseed oil, methamphetamines 3,29"
"On right heart catheterisation, a resting mean pulmonary arterial pressure of ≤20 mmHg is considered normal; when >20 mmHg, the diagnosis of pulmonary hypertension can be made 29, requiring further investigation of the clinical disease course."
"group 1: pulmonary arterial hypertension, e.g. idiopathic; heritable; associated with drugs and toxins; associated with connective tissue disease; HIV infection; portal hypertension, etc"
"group 1: pulmonary arterial hypertension, e.g. idiopathic; heritable; associated with drugs and toxins; associated with connective tissue disease; HIV infection; portal hypertension, etc"
"group 1: pulmonary arterial hypertension, e.g. idiopathic; heritable; associated with drugs and toxins; associated with connective tissue disease; HIV infection; portal hypertension, etc"
"group 1: pulmonary arterial hypertension, e.g. idiopathic; heritable; associated with drugs and toxins; associated with connective tissue disease; HIV infection; portal hypertension, etc"
"group 1: pulmonary arterial hypertension, e.g. idiopathic; heritable; associated with drugs and toxins; associated with connective tissue disease; HIV infection; portal hypertension, etc"
"group 2: pulmonary hypertension associated with left heart disease, e.g. heart failure; valvular heart disease"
"group 3: pulmonary hypertension associated with lung diseases and/or hypoxia, e.g. COPD and/or emphysema; interstitial lung disease, etc"
"group 5: pulmonary hypertension with unclear and/or multifactorial mechanisms, e.g. haematological disorders; sarcoidosis; pulmonary Langerhans cell histiocytosis; neurofibromatosis type 1; metabolic disorders; chronic renal failure"
"group 5: pulmonary hypertension with unclear and/or multifactorial mechanisms, e.g. haematological disorders; sarcoidosis; pulmonary Langerhans cell histiocytosis; neurofibromatosis type 1; metabolic disorders; chronic renal failure"
"group 5: pulmonary hypertension with unclear and/or multifactorial mechanisms, e.g. haematological disorders; sarcoidosis; pulmonary Langerhans cell histiocytosis; neurofibromatosis type 1; metabolic disorders; chronic renal failure"
"group 5: pulmonary hypertension with unclear and/or multifactorial mechanisms, e.g. haematological disorders; sarcoidosis; pulmonary Langerhans cell histiocytosis; neurofibromatosis type 1; metabolic disorders; chronic renal failure"
">29 mm diameter is often used as a general predictive cut-off 6,10,11,19; however, a 2011 study suggests 7:"
"Pulmonary hypertension can result from either increased pulmonary venous resistance (most common) or increased pulmonary arterial flow, such as with a left-to-right shunt 2. There are numerous known causes, including:"
"The WSPH/WHO classification grouping of pulmonary hypertension 28 is considered the current (c.2024) classification 29. There is a long list of subgroups, but the main entities include 29:"
"The ventricles (category A), pulmonary artery (category B), and right atrium and inferior vena cava (category C) may reveal suggestive findings of increased pressure/volume (a category is "positive" when one or more of the following findings are present)."
"High-resolution CT (HRCT) chest is indispensable for assessing the lung parenchyma and identifying possible causative processes (e.g. interstitial lung disease, COPD)."