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Lint: sarcomatoid-renal-cell-carcinoma

Litotes
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"On imaging, they are generally large masses, with irregular contours, and malignant-appearing, but do not have specific imaging features."

Line 2:106 · Consider using 'lack(s)' instead of 'not have'
Acronyms
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"The biology of sRCC is poorly understood. Since it generally develops from advanced renal cell cancer and often presents with metastases, it is difficult to treat effectively. Prognosis is worse than equivalent size and stage non-sarcomatous RCC."

Line 19:246 · 'RCC' has no definition. Spell it out if it's unfamiliar to the audience.