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Lint: hereditary-multiple-exostoses

Emphasis
warning

"Hereditary multiple exostoses is thought to result from EXT1, EXT2, or EXT3 gene mutations on chromosomes 8q24 (EXT1), 11p11-13 (EXT2), and 19p (EXT3) 4,5."

Line 14:60 · Italics should be used only in exceptional circumstances: '<em>EXT1</em>, <em>EXT2</em>, or <em>EXT3</em> gene mutations<sup> </sup>on chromosomes 8q24 (<em>EXT1</em>), 11p11-13 (<em>EXT2</em>), and 19p (<em>EXT3</em>'
Acronyms
warning

"Malignant transformation is more common than in sporadic cases, with transformation rates reported as high as 25% (lower rates of 3-5% have also been published) 3. The mnemonic GLAD PaST 1 lists the associations with sarcomatous transformation."

Line 29:195 · 'GLAD' has no definition. Spell it out if it's unfamiliar to the audience.
Headings Valid
warning

Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Complications"

Line 19:1 · "Complications" is under the wrong parent heading (found under "Treatment and prognosis").
Commas
suggestion

"Hereditary multiple exostoses can involve any bone in the body except for the calvarium 5. Common sites of involvement include the distal femur, proximal tibia, wrist and hands, humerus, ankle, pelvis, and ribs."

Line 12:158 · More than 5 commas in a single sentence might make it more difficult to read.
Oxford Comma
suggestion

"Hereditary multiple exostoses can involve any bone in the body except for the calvarium 5. Common sites of involvement include the distal femur, proximal tibia, wrist and hands, humerus, ankle, pelvis, and ribs."

Line 12:169 · Use the Oxford comma in 'tibia, wrist and hands'.