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Lint: infant-type-hemispheric-glioma-1

infant-type-hemispheric-glioma-1
En Dash
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"Infant-type hemispheric gliomas typically arise in the first year of life (range: 0–12 months) 2."

Line 5:87 · Use a hyphen-minus ('-') instead of an en-dash ('–').
Acronyms
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"Infant-type hemispheric gliomas belong to the family of "paediatric high-grade diffuse gliomas" of the 2021 WHO Classification of Tumours of the Central Nervous System 1. They have been recognised as a novel tumour type distinct from other paediatric high-grade gliomas, harbouring molecular mutations involving the receptor tyrosine kinases NTRK, ROS1, ALK, and MET."

Line 3:364 · 'NTRK' has no definition. Spell it out if it's unfamiliar to the audience.

"Infant-type hemispheric gliomas belong to the family of "paediatric high-grade diffuse gliomas" of the 2021 WHO Classification of Tumours of the Central Nervous System 1. They have been recognised as a novel tumour type distinct from other paediatric high-grade gliomas, harbouring molecular mutations involving the receptor tyrosine kinases NTRK, ROS1, ALK, and MET."

Line 3:383 · 'ALK' has no definition. Spell it out if it's unfamiliar to the audience.

"GFAP: positive"

Line 20:11 · 'GFAP' has no definition. Spell it out if it's unfamiliar to the audience.

"ALK: sometimes positive in the infant-type hemispheric glioma ALK-altered"

Line 21:11 · 'ALK' has no definition. Spell it out if it's unfamiliar to the audience.
Emphasis
warning

"Infant-type hemispheric gliomas belong to the family of "paediatric high-grade diffuse gliomas" of the 2021 WHO Classification of Tumours of the Central Nervous System 1. They have been recognised as a novel tumour type distinct from other paediatric high-grade gliomas, harbouring molecular mutations involving the receptor tyrosine kinases NTRK, ROS1, ALK, and MET."

Line 3:395 · Italics should be used only in exceptional circumstances: '<em>.</em>'

"infant-type hemispheric glioma, NTRK-altered"

Line 9:40 · Italics should be used only in exceptional circumstances: '<em>NTRK</em>'

"infant-type hemispheric glioma, ROS1-altered"

Line 10:40 · Italics should be used only in exceptional circumstances: '<em>ROS1</em>'

"infant-type hemispheric glioma, ALK-altered"

Line 11:40 · Italics should be used only in exceptional circumstances: '<em>ALK</em>'

"infant-type hemispheric glioma, MET-altered"

Line 12:40 · Italics should be used only in exceptional circumstances: '<em>MET</em>'

"ALK: sometimes positive in the infant-type hemispheric glioma ALK-altered"

Line 21:77 · Italics should be used only in exceptional circumstances: '<em>ALK</em>'

"diagnosis of these tumours generally requires detection of the fusion genes of tyrosine kinase NTRK1, NTRK2, NTRK3, ROS1, ALK, MET or, alternatively, a characteristic methylation profile 1-3"

Line 22:103 · Italics should be used only in exceptional circumstances: '<em>NTRK1</em>, <em>NTRK2</em>, <em>NTRK3</em>, <em>ROS1</em>, <em>ALK</em>, <em>MET </em>'

"More studies are needed to evaluate the survival rate and impact of targeted therapies. Infant-type hemispheric glioma ALK-altered subtype seems to have a better 5-year survival rate than the ROS1- and NTRK-altered subtypes 2."

Line 32:123 · Italics should be used only in exceptional circumstances: '<em>ALK</em>-altered subtype seems to have a better 5-year survival rate than the <em>ROS1- </em>and <em>NTRK</em>'
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Subtypes"

Line 7:1 · "Subtypes" is not a recognised heading for this article type.

"Immunophenotype and molecular alterations"

Line 18:1 · "Immunophenotype and molecular alterations" is not a recognised heading for this article type.
Commas
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"diagnosis of these tumours generally requires detection of the fusion genes of tyrosine kinase NTRK1, NTRK2, NTRK3, ROS1, ALK, MET or, alternatively, a characteristic methylation profile 1-3"

Line 22:117 · More than 5 commas in a single sentence might make it more difficult to read.
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