"Data for Libman-Sacks endocarditis comes from several case-controlled studies and cohort studies of patients with SLE. The prevalence of Libman-Sacks endocarditis in one prospective cohort study was estimated by transthoracic echocardiogram at around 11% 1. However, on post-mortem findings in older studies performed between 1950-1960 identified rates were as high as 35-65% of patients with SLE 2."
"The term describes vegetations on the cardiac valves that are sterile and doesn't show any signs of infection. LSE is characterised by the presence of autoantibodies, such as antiphospholipid antibodies. It has been postulated that there is selective deposition of complement and immune complexes along the endocardial surface leading to aggregation of platelets along the endocardial wall 5. The exact mechanism by which antiphospholipid antibodies are involved in the pathogenesis remains unclear."
"mainly associated with solid tumours such as adenocarcinoma of the pancreas, colon, ovary, lung, biliary, and prostate."
"increased prevalence rate of around 2.7% with solid tumours versus 0.47% other types of malignancy have been reported."
"may present in 6 to 11% of lupus patients."
"Data for Libman-Sacks endocarditis comes from several case-controlled studies and cohort studies of patients with SLE. The prevalence of Libman-Sacks endocarditis in one prospective cohort study was estimated by transthoracic echocardiogram at around 11% 1. However, on post-mortem findings in older studies performed between 1950-1960 identified rates were as high as 35-65% of patients with SLE 2."
"Further studies have demonstrated that three-dimensional echocardiography (3D-TEE, with TEE being the US-English acronym for TOE) is better at characterising valvular lesions (aortic and mitral valve lesions) 7. In these studies, 3D-TEE also detected more lesions in patients with cerebrovascular disease 7."
"Further studies have demonstrated that three-dimensional echocardiography (3D-TEE, with TEE being the US-English acronym for TOE) is better at characterising valvular lesions (aortic and mitral valve lesions) 7. In these studies, 3D-TEE also detected more lesions in patients with cerebrovascular disease 7."
"Further studies have demonstrated that three-dimensional echocardiography (3D-TEE, with TEE being the US-English acronym for TOE) is better at characterising valvular lesions (aortic and mitral valve lesions) 7. In these studies, 3D-TEE also detected more lesions in patients with cerebrovascular disease 7."
"Further studies have demonstrated that three-dimensional echocardiography (3D-TEE, with TEE being the US-English acronym for TOE) is better at characterising valvular lesions (aortic and mitral valve lesions) 7. In these studies, 3D-TEE also detected more lesions in patients with cerebrovascular disease 7."
Expected headings
"Associations"
"Echocardiography"