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Lint: low-grade-central-osteosarcoma

Emphasis
warning

"MDM2 amplification is a desirable criterion."

Line 13:4 · Italics should be used only in exceptional circumstances: '<em>MDM2</em>'
Oxford Comma
suggestion

"The diagnosis of low-grade central osteosarcomas is based on a combination of typical radiographic features, location, histology and immunohistochemistry. Due to similar features to fibrous dysplasia, the diagnosis is often difficult, even in the setting of an experienced multidisciplinary meeting 2."

Line 5:113 · Use the Oxford comma in 'location, histology and immunohistochemistry'.

"form, location and size"

Line 53:8 · Use the Oxford comma in 'form, location and size'.