"Macdonald criteria, published in 1990 3, are used to assess response to first-line treatment of glioblastoma, but have been largely superseded by the RANO criteria which have become the mainstay of assessment."
"Although extremely useful, Macdonald criteria have been shown to have a number of weaknesses, many of which have been addressed in the Response Assessment in Neuro-Oncology Criteria (RANO), published in 2010. Some of these weaknesses include 4:"
Expected headings
"Criteria"
"Complete response"
"Partial response"
"Stable disease"
"Progression"
"Weaknesses"