"The term derives from "μαλακία" (malakia: "soft") and "πλακία" (plakia: "slab/plaque"). The terms "malako"plakia and "malaco"plakia are used interchangeably as latinisations of "μαλακία". The term was first used by the German pathologist David Paul von Hansemann (1858-1920) 6, but the condition was first described by L Michaelis and D Gutmann in 1902 1."
"Histology is necessary for diagnosis. Von Hansemann foamy histiocytes with intra-cytoplasmic phagocytes containing incompletely digested bacteria. During the classic middle stage, basophilic intra-cytoplasmic laminated deposits containing iron and calcium salts, called Michaelis-Gutmann bodies are pathognomonic 2,5. Special stains are helpful."
"Histology is necessary for diagnosis. Von Hansemann foamy histiocytes with intra-cytoplasmic phagocytes containing incompletely digested bacteria. During the classic middle stage, basophilic intra-cytoplasmic laminated deposits containing iron and calcium salts, called Michaelis-Gutmann bodies are pathognomonic 2,5. Special stains are helpful."
"The term derives from "μαλακία" (malakia: "soft") and "πλακία" (plakia: "slab/plaque"). The terms "malako"plakia and "malaco"plakia are used interchangeably as latinisations of "μαλακία". The term was first used by the German pathologist David Paul von Hansemann (1858-1920) 6, but the condition was first described by L Michaelis and D Gutmann in 1902 1."
"In the most common setting, when the bladder is the site of disease, patients present with gross haematuria, lower urinary tract symptoms and recurrent urinary tract infection (most commonly with Escherichia coli ). Papules, plaques and ulceration on direct visualisation during flexible cystoscopy have been described 5. Shaggy masses can mimic neoplasia."