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Lint: mastocytosis

Units
error

"increased bone turnover, especially skull and long bones (99m Tc MDP bone scan)"

Line 70:71 · Put a space between the number and the unit in '99mTc'.
Isotope Notation
error

"increased bone turnover, especially skull and long bones (99m Tc MDP bone scan)"

Line 70:71 · Write the isotope as symbol-mass, e.g. F-18, not '99mTc'.
Sulfur Spelling
error

"increased haemopoietic activity (sulphur colloid scan)"

Line 71:41 · Use the 'f' spelling: 'sulfur' rather than 'sulphur'.
Acronyms
warning

"KIT-activating KIT point mutation at codon 816 or in other critical regions of KIT in bone marrow or another extracutaneous organ"

Line 10:8 · 'KIT' has no definition. Spell it out if it's unfamiliar to the audience.

"KIT-activating KIT point mutation at codon 816 or in other critical regions of KIT in bone marrow or another extracutaneous organ"

Line 10:23 · 'KIT' has no definition. Spell it out if it's unfamiliar to the audience.

"KIT-activating KIT point mutation at codon 816 or in other critical regions of KIT in bone marrow or another extracutaneous organ"

Line 10:87 · 'KIT' has no definition. Spell it out if it's unfamiliar to the audience.

"baseline serum tryptase concentration >20 ng/mL (in the case of an unrelated myeloid neoplasm, an elevated tryptase concentration does not count as an SM criterion); in the case of a known hereditary α-tryptasaemia (HαT), the tryptase level should be adjusted"

Line 12:159 · 'SM' has no definition. Spell it out if it's unfamiliar to the audience.

"Mastocytosis is a clonal disorder characterised by somatic mutations of the c-KIT proto-oncogene which encodes the receptor tyrosine kinase KIT (CD117) 15."

Line 30:82 · 'KIT' has no definition. Spell it out if it's unfamiliar to the audience.

"Mastocytosis is a clonal disorder characterised by somatic mutations of the c-KIT proto-oncogene which encodes the receptor tyrosine kinase KIT (CD117) 15."

Line 30:144 · 'KIT' has no definition. Spell it out if it's unfamiliar to the audience.

"Systemic mastocytosis with an associated haematological neoplasms (SM‐AHN): ~5% of cases of systemic mastocytosis are associated with myeloid malignancies:"

Line 34:78 · 'SM' has no definition. Spell it out if it's unfamiliar to the audience.

"Systemic mastocytosis with an associated haematological neoplasms (SM‐AHN): ~5% of cases of systemic mastocytosis are associated with myeloid malignancies:"

Line 34:81 · 'AHN' has no definition. Spell it out if it's unfamiliar to the audience.
Colons
warning

"mast cells in the bone marrow, blood, or another extracutaneous organ express one or more of the following: CD2, CD25, or CD30"

Line 11:114 · The first word after a colon should almost always be lowercase. In this case, it's not: ': CD2, CD25'.
List Caps
warning

"B, high burden of disease (without organ dysfunction)"

Line 49:4 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.
Headings Valid
warning

Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Associations"

Line 33:1 · "Associations" is under the wrong parent heading (found under "Pathology").

"Skeletal, soft tissues"

Line 62:1 · "Skeletal, soft tissues" is not a recognised heading for this article type.

"Abdominal"

Line 75:1 · "Abdominal" is not a recognised heading for this article type.

"Pulmonary"

Line 87:1 · "Pulmonary" is not a recognised heading for this article type.

"CNS"

Line 94:1 · "CNS" is not a recognised heading for this article type.
Semicolons
suggestion

"baseline serum tryptase concentration >20 ng/mL (in the case of an unrelated myeloid neoplasm, an elevated tryptase concentration does not count as an SM criterion); in the case of a known hereditary α-tryptasaemia (HαT), the tryptase level should be adjusted"

Line 12:172 · Use semicolons judiciously.

"cutaneous mastocytosis, more common in children; adults with cutaneous manifestations usually have systemic disease 14"

Line 44:55 · Use semicolons judiciously.
There Is
suggestion

"There is considerable heterogeneity in the presentation of mastocytosis, and in the rate of disease progression. Disease can be local and mild or systemic and life-threatening. Skin and bone marrow are most commonly affected. Clinical features include:"

Line 16:4 · Don't start a sentence with 'There is'.
Oxford Comma
suggestion

"nausea, vomiting and diarrhoea"

Line 22:8 · Use the Oxford comma in 'nausea, vomiting and diarrhoea'.

"In systemic mastocytosis, abnormal proliferation and microscopic infiltration of mast cells variably involve the skin, bone marrow, gastrointestinal tract, lymph nodes, liver and spleen."

Line 32:166 · Use the Oxford comma in 'nodes, liver and spleen'.

"effusions, pleural and pericardial"

Line 89:8 · Use the Oxford comma in 'effusions, pleural and pericardial'.