"Studies have found a huge variation in the incidence of Nelson syndrome. Incidence rates have varied from 6-47% in adults to 25-66% in paediatric populations undergoing bilateral adrenalectomy 1. It has been identified that the incidence increases with follow-up time 1. The presence of high basal adrenocorticotropic hormone (ACTH) is the best predictor for development of Nelson syndrome 1."
"The tumours stain positive for ACTH and MSH, similar to pituitary adenomas observed in Cushing disease. The tumours are PAS positive."
"History and etymology"