"although the skin is primarily involved, many other organs (e.g. lungs, heart, diaphragm, liver, kidneys, oesophagus, and skeletal muscles) can also be involved, eventually leading to death 7"
"New cases of nephrogenic systemic fibrosis are still being reported, in 2021 a patient developed it 6 months after GBCA administration; and then in 2026 an elderly female with stage 3a chronic kidney disease incurred biopsy-proven nephrogenic systemic fibrosis 14,17."
"American College of Radiology recommendations"
Expected headings
"Screening"
"Recommendations"
"American College of Radiology recommendations"
"Previous advice"
"concurrent infarcted/ischaemic tissue (e.g. peripheral arterial thromboembolism)"
"history of renal disease: renal transplant (20% develop NSF), dialysis, single kidney, renal malignancy, renal surgery; should have eGFR checked"
"New cases of nephrogenic systemic fibrosis are still being reported, in 2021 a patient developed it 6 months after GBCA administration; and then in 2026 an elderly female with stage 3a chronic kidney disease incurred biopsy-proven nephrogenic systemic fibrosis 14,17."
""When contrast-enhanced MR imaging is requested for a patient with renal insufficiency who is hospitalised due to major surgery, major infection, or a thrombotic vascular event, alternative imaging is indicated to avoid the use of gadolinium-based contrast agents; this decision should be made after consultation with the referring service and the patient" 1."
"although the skin is primarily involved, many other organs (e.g. lungs, heart, diaphragm, liver, kidneys, oesophagus, and skeletal muscles) can also be involved, eventually leading to death 7"
"A deep dermal biopsy is required, however, findings are non-specific, showing thickened collagen bundle, mucin deposition, spindle cell proliferation, and CD3+ fibroblasts."
"There is only one case report of histologically-proven nephrogenic systemic fibrosis in a patient with no documented history of exposure to gadolinium-based contrast agents 13."
"There is no consistently effective therapy for nephrogenic systemic fibrosis. Adjunct treatment options include:"
"extracorporeal photopheresis, plasmapheresis, immunoglobulin therapy, steroids and other immunosuppressive agents"