"The exact cause is unknown but is believed due to be a combination of ischaemia, infection (especially with cytomegalovirus, Pseudomonas aeruginosa), mucosal haemorrhage, and perhaps neoplastic infiltration 1."
"For terminal ileitis consider the differential diagnosis of a terminal ileitis."
"Typhlitis, also known as neutropenic colitis, is a necrotising inflammatory condition that typically originates in the caecum and often extends into the ascending colon, appendix or terminal ileum by the time of presentation. In general, patients are immunocompromised and usually neutropenic."
"Typhlitis was first described in children with leukaemia and severe neutropenia (seen with an absolute neutrophil count"
"Clinically, patients with typhlitis present with a mixture of localised and systemic symptoms including a fever, chills, nausea, vomiting, diarrhoea, abdominal pain, tenderness and a distended abdomen. Peritoneal irritation and occult bloody stools may be present. Pain in the right lower quadrant may mimic appendicitis."
"Clinically, patients with typhlitis present with a mixture of localised and systemic symptoms including a fever, chills, nausea, vomiting, diarrhoea, abdominal pain, tenderness and a distended abdomen. Peritoneal irritation and occult bloody stools may be present. Pain in the right lower quadrant may mimic appendicitis."
"Transabdominal ultrasonography demonstrating bowel wall thickening in an appropriate clinical context has been used to supplement the clinical diagnosis of typhlitis. Bowel wall thickening may be eccentric or concentric and is often dramatic; caecal wall measurements are often above 1 cm in severe cases. Sonographic findings are relatively non-specific, but are especially helpful in high pretest probability patients, and may also address the possibility of cholecystitis which, especially in the immunocompromised, has an atypical presentation 13."
"Bowel wall thickening >4 mm is virtually always demonstrated; other features consistent with the diagnosis include:"