"Signal characteristics of the affected region(s) include:"
"T1: mildly or moderately hypointense"
"T2/FLAIR: hyperintense, sparing the periphery and corticospinal tracts"
"PD: hyperintense"
"DWI: hyperintense"
"ADC: signal low or signal loss"
"T1 C+ (Gd): usually there is no enhancement, but some authors report that it may occur 5,6"
"Osmotic demyelination syndrome is the preferred term, replacing central pontine myelinolysis (CPM), recognising that extrapontine structures can also be affected, previously known as extrapontine myelinolysis (EPM)."
"Osmotic demyelination syndrome is the preferred term, replacing central pontine myelinolysis (CPM), recognising that extrapontine structures can also be affected, previously known as extrapontine myelinolysis (EPM)."
"The initial description of this pathology as central pontine myelinolysis was made by Adams et al. in 1959 in a a population of patients with chronic alcohol use 2."
Expected headings
"PET"
"rapid electrolyte correction (e.g. correction of hyponatraemia)"
"Similar signal changes are seen in other extrapontine regions of the brain, including but not limited to, in decreasing order of frequency, the cerebellum, lateral geniculate body, external capsule, extreme capsule, hippocampus, putamen, cerebral cortex, thalamus, and caudate nucleus 15."