"In 1930, James Papez (1883-1958) 5, an American neuroanatomist, suggested that the cognitive activity in the cortex affects the expression of emotions through connections to the hypothalamus and hippocampus. In Papez’s proposal, the hypothalamus regulates the autonomic nervous system activity during the expressions of emotions. Subsequently Paul MacLean modified Papez’s proposal to include the basal forebrain, amygdala and prefrontal cortex, and named it the limbic system 1,2. It is well-established that the Papez circuit has a more significant role in memory functions than in emotions 3."
"In a more succinct format 2: hippocampus → fornix → mammillary body → mammillothalamic fibres→ thalamus (anterior nucleus) → cingulum→ entorhinal cortex → hippocampal formation."
Expected headings
"Pathway"
"Information from cortical association areas passes to the hippocampus via the cingulate gyrus, cingulum and parahippocampal gyrus. After information processing in the hippocampus, signals are transferred to the hypothalamus (mammillary body) via the fornix. Completion of the circuit and feedback to the cortex is accomplished through mammillothalamic fibres, relaying information from the hypothalamus to the anterior nucleus of the thalamus. The anterior nucleus of the thalamus projects fibres to the cingulate gyrus, cingulum and parahippocampal gyrus back to the hippocampus."
"Information from cortical association areas passes to the hippocampus via the cingulate gyrus, cingulum and parahippocampal gyrus. After information processing in the hippocampus, signals are transferred to the hypothalamus (mammillary body) via the fornix. Completion of the circuit and feedback to the cortex is accomplished through mammillothalamic fibres, relaying information from the hypothalamus to the anterior nucleus of the thalamus. The anterior nucleus of the thalamus projects fibres to the cingulate gyrus, cingulum and parahippocampal gyrus back to the hippocampus."
"In 1930, James Papez (1883-1958) 5, an American neuroanatomist, suggested that the cognitive activity in the cortex affects the expression of emotions through connections to the hypothalamus and hippocampus. In Papez’s proposal, the hypothalamus regulates the autonomic nervous system activity during the expressions of emotions. Subsequently Paul MacLean modified Papez’s proposal to include the basal forebrain, amygdala and prefrontal cortex, and named it the limbic system 1,2. It is well-established that the Papez circuit has a more significant role in memory functions than in emotions 3."