"Perihilar cholangiocarcinoma staging is, for prognostication, most commonly conducted using the TNM staging classification of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC). As of 2018, the staging criteria are in their 8th edition and reflected below 1. These criteria apply to hilar/perihilar cholangiocarcinomas (Klatskin tumour), while cancers of the intrahepatic and distal bile ducts are staged differently."
"Perihilar cholangiocarcinoma staging is, for prognostication, most commonly conducted using the TNM staging classification of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC). As of 2018, the staging criteria are in their 8th edition and reflected below 1. These criteria apply to hilar/perihilar cholangiocarcinomas (Klatskin tumour), while cancers of the intrahepatic and distal bile ducts are staged differently."
"Perihilar cholangiocarcinoma staging is, for prognostication, most commonly conducted using the TNM staging classification of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC). As of 2018, the staging criteria are in their 8th edition and reflected below 1. These criteria apply to hilar/perihilar cholangiocarcinomas (Klatskin tumour), while cancers of the intrahepatic and distal bile ducts are staged differently."
"TX: primary tumour cannot be assessed"
"NX: regional lymph nodes cannot be assessed"
"Primary tumour (T)"
"Regional lymph node (N)"
"Distant metastases (M)"
"TX: primary tumour cannot be assessed"
"TX: primary tumour cannot be assessed"
"T0: no evidence of primary tumour"
"Tis: carcinoma in situ/high-grade dysplasia"
"T1: tumour confined to the bile duct, with extension up to the muscle layer or fibrous tissue"
"T2:"
"T2a: tumour invades beyond the wall of the bile duct to surrounding adipose tissue"
"T2b: tumour invades adjacent hepatic parenchyma"
"T3: tumour invades unilateral branches of the portal vein or hepatic artery"
"T4:"
"NX: regional lymph nodes cannot be assessed"
"N0: no regional lymph node metastasis"
"N1: 1-3 positive regional lymph nodes"
"N2: 4 or more positive regional lymph nodes"
"cM0: no evidence of metastases"
"cM1: distant metastasis"
"pM1: distant metastasis, microscopically confirmed"
"stage 0"
"Tis, N0, M0"
"stage IT1, N0, M0"
"stage II[T2a, T2b], N0, M0"
"stage IIIAT3, N0, M0"
"stage IIIBT4, N0, M0"
"stage IIIC[Any T], N1, M0"
"stage IVA[Any T], N2, M0"
"stage IVB[Any T], [Any N], M1"
"Tis: carcinoma in situ/high-grade dysplasia"
"T2a: tumour invades beyond the wall of the bile duct to surrounding adipose tissue"
"T2b: tumour invades adjacent hepatic parenchyma"
"Tis: carcinoma in situ/high-grade dysplasia"
Expected headings
"Primary tumour (T)"
"Regional lymph node (N)"
"Distant metastases (M)"
"Stage groups"