"Location "
"T1: low to intermediate signal vs muscle"
"T2/STIR: high signal intensity with punctate or curvilinear signal voids indicating matrix mineralisation"
"T1 C+ (Gd): peripheral and septal enhancement"
"The term ‘juxta-cortical chondrosarcoma’ is no longer recommended 1."
"IDH1 and IDH2 mutations which can be found in conventional central chondrosarcoma are expressed in a subset of cases. EXT1 is expressed normally without mutations that are found in secondary peripheral chondrosarcomas 1,3. There might be dysregulations of RB1 signalling pathways. Unlike in parosteal osteosarcoma CDK4 or MDM2 amplification is absent 1,3."
Expected headings
"Location "
"Plain radiograph/CT"
"Signal characteristics"
"Nuclear medicine"
"Complications"
"Periosteal chondrosarcomas, previously also known as juxta-cortical chondrosarcomas, are cartilagineous or chondroid matrix-generating neoplasms originating in close association with the periosteum from the bony surface 1-3."
"The diagnosis of periosteal chondrosarcoma is made by a combination of clinical information, location and origin of the tumour as well as the invasion of the bony cortex or tumour size and can be eventually confirmed by histology 1-4."
"periosteal osteosarcoma: osteoid areas, sunburst or hair-on-end pattern, no IDH mutations"
"History and etymology"