"Perry syndrome is a rare, progressive, hereditary neurodegenerative movement disorder and TDP-43 proteinopathy."
"Affected regions of the brain in Perry syndrome unsurprisingly demonstrate neuronal loss and gliosis 1-3. Furthermore, on immunostaining, neurones may have abnormal transactive response DNA-binding protein of 43 kDa (TDP-43)-positive cytoplasmic inclusions 1-4. Thus, Perry syndrome is considered a TDP-43 proteinopathy."
"Affected regions of the brain in Perry syndrome unsurprisingly demonstrate neuronal loss and gliosis 1-3. Furthermore, on immunostaining, neurones may have abnormal transactive response DNA-binding protein of 43 kDa (TDP-43)-positive cytoplasmic inclusions 1-4. Thus, Perry syndrome is considered a TDP-43 proteinopathy."
"In addition to these features, patients many have a wide array of other neurological symptoms, such as presence of frontal signs, oculomotor disorders, dysphagia, dementia, and autonomic dysfunction 1."
"History and etymology"