"midbrain to pons area ratio (figure 1): reduced area ratio on the midline sagittal plane to approximately 0.12 (normal ~ 0.24) 4"
"T2: diffuse high-signal lesions in"
"PSP-speech/language disorder (PSP-SL)"
"I-123 ioflupane SPECT: dopamine active transporter imaging shows loss of the normal comma- or crescent-shaped tracer uptake in the striatum. Instead, a period- or oval-shaped uptake is seen within the caudate nucleus head without tracer uptake in the putamen; quantitative assessment reveals reduced uptake in the putamen compared to norms"
"F-18 FDG PET: frontal lobe and/or midbrain hypometabolism support the diagnosis 11; the frontal areas particularly involved are the premotor, precentral, and prefrontal regions and anterior cingulate 11"
"predominantly affects middle cerebellar peduncles, cerebellum and pons (hot cross bun sign)"