"Pituitary carcinomas are composed of adenohypophysial cells and do not show obvious microscopic features of malignancy. The majority are hormonally active 1-3. They sometimes demonstrate elevate mitotic index (e.g. Ki67 > 10%) 5."
"Due to the rarity of these tumours, no robust prognostic information is available. Patients generally tend to have a poor prognosis with a reported mean survival time between 1 to 2 years 2, although, protracted survival has also been reported 5."
"Treatment depends on location and and extent of disease and the specifics of the tumour. External beam radiotherapy, chemotherapy (e.g. temozolomide, everolimus (mTOR inhibitor), sunitinib, bevacizumab) have been used. If the tumour is positive for somatostatin receptors then somatostatin analogues and peptide receptor radionuclide therapy (PRRT) can be used 5."
Expected headings
"PET"