"The criteria with most widespread use is the European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) 2012 classification criteria, which uses clinical and ultrasound criteria 10:"
"The criteria with most widespread use is the European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) 2012 classification criteria, which uses clinical and ultrasound criteria 10:"
"abnormal CRP and/or ESR"
"absence of RF or ACPA (anti-CCP) (2 points)"
"absence of RF or ACPA (anti-CCP) (2 points)"
"raised inflammatory markers (e.g. ESR, CRP) 6"
"Extra-musculoskeletal manifestations in polymyalgia rheumatica, beyond those of associated giant cell arteritis, are very rare, but may include interstitial lung disease 11."
"The aetiopathogenesis of polymyalgia rheumatica is unknown 6. However, it is believed that both genetic (e.g. HLA-DRB1) and environmental (e.g. infection) factors play a role 6."
"Importantly, in patients who do not have an expected dramatically positive response to corticosteroids, an underlying malignancy causing paraneoplastic polymyalgia rheumatica-like symptoms, or an alternative diagnosis, should be suspected 6."
Expected headings
"Associations"
"Polymyalgia rheumatica is the most common inflammatory rheumatic condition in older adults 1, almost exclusively occurring in the >50 years demographic 6. The mean age of onset is 73 years, with the incidence increasing with age 6. There is a female preponderance 6. Geographically, it is most common in northern Europe, such as in Scandinavian countries 6."
"constitutional symptoms (e.g. fatigue, weight loss)"
"Several characteristic areas of hypermetabolic activity are seen on FDG PET-CT which likely reflect bursitis, synovitis, or tenosynovitis 6. Characteristic locations of hypermetabolic activity include the shoulder joints, sternoclavicular joints, interspinous regions, hip joints, prepubic regions, ischial tuberosities, and knee joints 3,4,6. Smaller joints of the wrist and hand are less commonly affected 3. If there is avid vascular FDG uptake, then concurrent giant cell arteritis should be strongly suspected 6."