"T1: low to intermediate signal intensity"
"T2: variably high signal intensity"
"T2FS/STIR: variably high signal intensity"
"T1 C+ (Gd): homogeneous to a mildly heterogeneous enhancement"
"positivity of ERG, FOSB and keratins"
"positivity of ERG, FOSB and keratins"
"FOSB gene rearrangement"
"Immunohistochemistry stains are usually positive for keratin, ERG FLI1 and FOSB. CD31 and smooth muscle actin are other markers that might be expressed. CD34 is usually negative 1-3."
"Immunohistochemistry stains are usually positive for keratin, ERG FLI1 and FOSB. CD31 and smooth muscle actin are other markers that might be expressed. CD34 is usually negative 1-3."
"FOSB gene rearrangements with a fusion of the SERPINE1-FOSB or ACTB-FOSB have been demonstrated. Both gene fusions show similar clinical and pathological features, although solitary lesions seem to be more common with the ACTB-FOSB gene fusion 1,2."
"FOSB gene rearrangements with a fusion of the SERPINE1-FOSB or ACTB-FOSB have been demonstrated. Both gene fusions show similar clinical and pathological features, although solitary lesions seem to be more common with the ACTB-FOSB gene fusion 1,2."
"T1: low to intermediate signal intensity"
"T2: variably high signal intensity"
"T2FS/STIR: variably high signal intensity"
"T1 C+ (Gd): homogeneous to a mildly heterogeneous enhancement"
Expected headings
"Signal characteristics"
"positivity of ERG, FOSB and keratins"
"form, location and size"
"relationship to bones, tendons and joints"
"Due to the rare occurrence, optimal management is still somewhat unclear. Treatment usually consists of wide surgical excision possibly with adjunctive chemo- and/or radiotherapy. Local recurrence or appearance of additional nodules is common and occurs in about 60% of patients with a short recurrence time interval of 1-2 years. Lymph node metastases or distant metastases to lungs, bones and soft tissues are infrequent but can occur even decades after the initial presentation 1-3."