"It is named after Cecilio Félix Romaña (1899-1997), an Argentinian physician, who first described the phenomenon 2."
"Romaña sign, also known as the periorbital swelling syndrome, refers to unilateral periorbital swelling, palpebral oedema and conjunctivitis seen 1-2 weeks following infection with Trypanosoma cruzi (causative agent in Chagas disease) due to inoculation via the conjunctiva, for example by rubbing the eyes 1-3. Periorbital swelling can also be caused by allergic reaction to vector saliva or faeces (e.g. triatomine), so infection cannot be assumed 3."