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Lint: sapho-syndrome

sapho-syndrome
Strong List Colon Position
error

"S: synovitis"

Line 3:8 · When enboldening an intro, the colon should not be bold. '<strong>S: </strong>'

"A: acne"

Line 4:8 · When enboldening an intro, the colon should not be bold. '<strong>A: </strong>'

"P: pustulosis"

Line 5:8 · When enboldening an intro, the colon should not be bold. '<strong>P: </strong>pustulosis'

"H: hyperostosis"

Line 6:8 · When enboldening an intro, the colon should not be bold. '<strong>H: </strong>hyperostosis'

"O: osteitis"

Line 7:8 · When enboldening an intro, the colon should not be bold. '<strong>O: </strong>'
Acronyms
warning

"The SAPHO syndrome is a rare osteoarticular and cutaneous condition that is manifested by a combined occurrence of 2:"

Line 1:16 · 'SAPHO' has no definition. Spell it out if it's unfamiliar to the audience.

"SAPHO has a reported prevalence of 1 in 10,000 adults 15. It classically presents in young to middle-aged adults 15. Presentation in the paediatric population is not uncommon. There may be a slightly higher female predilection in younger ("

Line 10:4 · 'SAPHO' has no definition. Spell it out if it's unfamiliar to the audience.

"The aetiology of SAPHO syndrome is unknown, with an autoinflammatory disease pathogenesis favoured 13. Cutibacterium acnes (previously known as Propionibacterium acnes), an anaerobic skin commensal, has been reported as a causative agent or environmental trigger but is not thought to be a major aetiological factor 8,11-13."

Line 26:21 · 'SAPHO' has no definition. Spell it out if it's unfamiliar to the audience.

"Plain radiograph is non-specific, but SAPHO syndrome can be suspected if present with the other clinical findings:"

Line 34:42 · 'SAPHO' has no definition. Spell it out if it's unfamiliar to the audience.

"SAPHO has a waxing and waning course 13. Evidence for treatment options for SAPHO syndrome is limited, with no standardised treatment regimen 13,15. NSAIDs are first-line for pain, and bisphosphonates (usually intravenous pamidronate) are the most consistently effective for bone disease but not for skin disease 6,13. Methotrexate and TNF inhibitors are used for refractory disease and help both bone and, to a lesser extent, skin, while tofacitinib shows early promise for refractory skin and nail involvement 13."

Line 50:4 · 'SAPHO' has no definition. Spell it out if it's unfamiliar to the audience.

"SAPHO has a waxing and waning course 13. Evidence for treatment options for SAPHO syndrome is limited, with no standardised treatment regimen 13,15. NSAIDs are first-line for pain, and bisphosphonates (usually intravenous pamidronate) are the most consistently effective for bone disease but not for skin disease 6,13. Methotrexate and TNF inhibitors are used for refractory disease and help both bone and, to a lesser extent, skin, while tofacitinib shows early promise for refractory skin and nail involvement 13."

Line 50:91 · 'SAPHO' has no definition. Spell it out if it's unfamiliar to the audience.

"SAPHO has a waxing and waning course 13. Evidence for treatment options for SAPHO syndrome is limited, with no standardised treatment regimen 13,15. NSAIDs are first-line for pain, and bisphosphonates (usually intravenous pamidronate) are the most consistently effective for bone disease but not for skin disease 6,13. Methotrexate and TNF inhibitors are used for refractory disease and help both bone and, to a lesser extent, skin, while tofacitinib shows early promise for refractory skin and nail involvement 13."

Line 50:373 · 'TNF' has no definition. Spell it out if it's unfamiliar to the audience.

"For bony features in children, consider chronic recurrent multifocal osteomyelitis (CRMO), although there is controversy over whether CRMO and SAPHO are the same condition presenting at different ages 13,14."

Line 52:154 · 'SAPHO' has no definition. Spell it out if it's unfamiliar to the audience.
List Caps
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"S: synovitis"

Line 3:16 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

"A: acne"

Line 4:16 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

"P: pustulosis"

Line 5:16 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

"H: hyperostosis"

Line 6:16 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.

"O: osteitis"

Line 7:16 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.
Emphasis
warning

"The aetiology of SAPHO syndrome is unknown, with an autoinflammatory disease pathogenesis favoured 13. Cutibacterium acnes (previously known as Propionibacterium acnes), an anaerobic skin commensal, has been reported as a causative agent or environmental trigger but is not thought to be a major aetiological factor 8,11-13."

Line 26:118 · Italics should be used only in exceptional circumstances: '<em>Cutibacterium acnes</em> (previously known as <em>Propionibacterium acnes</em>'
Headings Valid
warning

Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Associations"

Line 27:1 · "Associations" is under the wrong parent heading (found under "Pathology").
Oxford Comma
suggestion

"joint pain, swelling and tenderness affecting the anterior chest wall (~90%), sacroiliac joints, spine, and less commonly (~30%) peripheral large joints 13,14"

Line 14:14 · Use the Oxford comma in 'pain, swelling and tenderness'.

"osteitis, hyperostosis and hypertrophy of the medial ends of the clavicles, sternum and upper ribs and ultimately ankylosis"

Line 23:8 · Use the Oxford comma in 'osteitis, hyperostosis and hypertrophy'.

"osteitis, hyperostosis and hypertrophy of the medial ends of the clavicles, sternum and upper ribs and ultimately ankylosis"

Line 23:80 · Use the Oxford comma in 'clavicles, sternum and upper'.
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