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Lint: superparamagnetic-iron-oxide

Adjectival Hyphens
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"The main agent used is ferumoxytol (Feraheme), an ultrasmall SPIO, which is otherwise used to treat iron deficiency anaemia in patients with chronic kidney disease. Knowledge of this other use is important as administration of ferumoxytol (within 3 months) can complicate MRI interpretation, manifesting as susceptibility artifact, pre-gadolinium contrast T1 hyperintensity, and T2 hypointensity in the vasculature 1,2."

Line 2:357 · Only use medical adjectival hyphens where the letters at the end and start of the compound word are the same, e.g. post-transplant. In this case, don't use the hyphen: 'pre-gadolinium'.
Acronyms
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"The main agent used is ferumoxytol (Feraheme), an ultrasmall SPIO, which is otherwise used to treat iron deficiency anaemia in patients with chronic kidney disease. Knowledge of this other use is important as administration of ferumoxytol (within 3 months) can complicate MRI interpretation, manifesting as susceptibility artifact, pre-gadolinium contrast T1 hyperintensity, and T2 hypointensity in the vasculature 1,2."

Line 2:72 · 'SPIO' has no definition. Spell it out if it's unfamiliar to the audience.

"Previously available SPIO agents for MRI include:"

Line 3:25 · 'SPIO' has no definition. Spell it out if it's unfamiliar to the audience.
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Biodistribution"

Line 8:1 · "Biodistribution" is not a recognised heading for this article type.