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Lint: synovioma

Uncomparables
error

"The biphasic variant is composed of glandular components (which may be dominant or hidden) and spindle cells. Spindle cells are quite uniform and arranged in fascicular pattern."

Line 8:132 · 'quite uniform' is not comparable
Adjectival Hyphens
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"Treatment involves a combination of surgery and usually adjuvant radiotherapy +/- chemotherapy. Radiotherapy is particularly useful in treating tumours where an adequate clear margin cannot be achieved, and ideally, radiotherapy is administered pre-operatively."

Line 88:249 · Only use medical adjectival hyphens where the letters at the end and start of the compound word are the same, e.g. post-transplant. In this case, don't use the hyphen: 'pre-operatively.'.
Acronyms
warning

"Monophasic synovial sarcoma composed of spindle cells and is quite resemble to MPNST, fibrosarcoma, mesenchymal chondrosarcoma and cellular SFT. For establishing a correct diagnosis, an IHC study for keratin and EMA is very helpful. Nearly 90% of monophasic variants are at least focally positive for keratin or EMA."

Line 9:144 · 'SFT' has no definition. Spell it out if it's unfamiliar to the audience.

"Monophasic synovial sarcoma composed of spindle cells and is quite resemble to MPNST, fibrosarcoma, mesenchymal chondrosarcoma and cellular SFT. For establishing a correct diagnosis, an IHC study for keratin and EMA is very helpful. Nearly 90% of monophasic variants are at least focally positive for keratin or EMA."

Line 9:216 · 'EMA' has no definition. Spell it out if it's unfamiliar to the audience.

"Monophasic synovial sarcoma composed of spindle cells and is quite resemble to MPNST, fibrosarcoma, mesenchymal chondrosarcoma and cellular SFT. For establishing a correct diagnosis, an IHC study for keratin and EMA is very helpful. Nearly 90% of monophasic variants are at least focally positive for keratin or EMA."

Line 9:316 · 'EMA' has no definition. Spell it out if it's unfamiliar to the audience.

"SS18-SSX fusion antibody is 95% sensitive and specific for synovial sarcoma.10"

Line 10:9 · 'SSX' has no definition. Spell it out if it's unfamiliar to the audience.
EG List And
warning

"The most common location for these tumours is within the deep soft tissues adjacent to large joints, e.g. knee and popliteal fossa. While these tumours arise near joints, it is rare for them to arise from the joint itself and despite their name, they do not arise from synovial structures, e.g. joints, tendon sheaths and bursae."

Line 12:308 · An e.g. list gives selected examples, so it should not end with 'and' or 'or': 'e.g. joints, tendon sheaths and'.
Prefix Hyphens
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"Non-specific findings, with a heterogeneous predominantly hypoechoic mass. Intra-lesion flow is usually associated with more aggressive lesions."

Line 57:79 · A prefix takes a hyphen only to avoid a duplicate letter: 'Intra-lesion'.
Ranges
warning

"Overall 5-year survival is between 36-76%. Both local recurrence (30-50%) and distant metastases are frequent (40-70%), most commonly to the lungs as cannonball metastases (~80%), bones (~15%), regional lymph nodes (~10%), followed by chest wall/abdomen (~7.5%) 7,8."

Line 117:31 · Don't add words such as 'from' or 'between' to describe a range of numbers.
Commas
suggestion

"lung 2, kidney, prostate, oesophagus, heart, pericardium, pleura"

Line 35:29 · More than 5 commas in a single sentence might make it more difficult to read.