"Secondary osteosarcoma occurs in the elderly, usually secondary to malignant degeneration of Paget disease, extensive bone infarcts, post-radiotherapy for other conditions, osteochondroma, and osteoblastoma."
"Codman triangle"
"Ewing sarcoma"
"FDG PET is better than bone scintigraphy for detecting bone metastases. It will show increased SUV at sites of distant metastases. As there is no definite cutoff value for SUV level, it can be used in follow-up to evaluate the response to chemotherapy 12."
"FDG PET is better than bone scintigraphy for detecting bone metastases. It will show increased SUV at sites of distant metastases. As there is no definite cutoff value for SUV level, it can be used in follow-up to evaluate the response to chemotherapy 12."
Expected headings
"Bone scintigraphy"
"FDG PET"
"wide zone of transition, permeative or moth-eaten appearance"
"If a limb-salvage procedure is feasible, a course of multidrug chemotherapy precedes surgery to downstage the tumour 15, followed by wide resection of the bone and insertion of an endoprosthesis. The outcome depends on factors such as age, sex, site, size, and type, but the most important predictor is the histologic degree of necrosis after induction chemotherapy; 90% histologic necrosis is associated with a much better prognosis 6. The 5-year survival rate after adequate therapy is approximately 60-80% in the setting of localised disease 4,16. Outcomes for metastatic disease remain significantly worse 16."