"The T-cell and natural killer T-cell lymphomas are a large group of rare and aggressive lymphoid neoplasms derived from T or natural killer (NK) cells. In the 5th edition (2022) of the WHO classification of haematolymphoid tumours, thirty-six entities are recognised 2. These non-Hodgkin lymphomas can involve various organs, including the lymph nodes, spleen and extranodal sites including skin, gastrointestinal tract and central nervous system 1,2."
"The clinical presentation of T-cell and NK/T-cell lymphomas varies depending on the site of involvement. Patients may present with lymphadenopathy, fever, night sweats, weight loss, or B-symptoms. Skin involvement can present as a rash or ulceration, and gastrointestinal involvement can cause abdominal pain, diarrhoea, or bleeding. Central nervous system involvement has a non-specific presentation including headaches, focal neurological deficits, seizures and features of increased intracranial pressure 1. Involvement of the nasal cavity (as in nasal T-cell/NK-cell lymphoma) typically presents with nasal blockage, bleeding or discharge or constitutional symptoms 4."
"The clinical presentation of T-cell and NK/T-cell lymphomas varies depending on the site of involvement. Patients may present with lymphadenopathy, fever, night sweats, weight loss, or B-symptoms. Skin involvement can present as a rash or ulceration, and gastrointestinal involvement can cause abdominal pain, diarrhoea, or bleeding. Central nervous system involvement has a non-specific presentation including headaches, focal neurological deficits, seizures and features of increased intracranial pressure 1. Involvement of the nasal cavity (as in nasal T-cell/NK-cell lymphoma) typically presents with nasal blockage, bleeding or discharge or constitutional symptoms 4."