"acquisition times are relatively long (more than 5 minutes) 3."
"retrograde arterial flow may be obscured if venous saturation bands have been applied."
"Time of flight angiography (TOF) is an MRI technique to visualise flow within vessels, without the need to administer contrast. It is a T1-weighted gradient-echo sequence exploiting flow-related enhancement of blood entering an imaging slice or volume to generate signal."
"T1-weighted MRI sequences rely on partial saturation of the tissues being imaged to create differences in the returned signal. When repeated radiofrequency pulses are applied with short repetition time (TR), protons do not have sufficient time to fully recover their longitudinal magnetisation (Mz). The degree of recovery depends on the T1 relaxation time of each tissue, thereby generating image contrast."
"Time-of-flight MRA exploits this principle by using very short TR pulses to deliberately saturate stationary tissues, thereby markedly reducing the T1 signal of all tissues and thereby accentuating flow-related enhancement of blood flowing into the volume. However, as this blood enters, it immediately starts to become saturated, and after some time, it too loses its signal."
"short TR"
"The term enhancement in MRI is most strictly applied to increased signal intensity resulting from the administration of positive contrast media (e.g. gadolinium-based agents). Consequently, some purists argue that flow-related high signal is a more accurate descriptor for this phenomenon. That notwithstanding, much of the literature uses the term flow-related enhancement."
"T1-weighted MRI sequences rely on partial saturation of the tissues being imaged to create differences in the returned signal. When repeated radiofrequency pulses are applied with short repetition time (TR), protons do not have sufficient time to fully recover their longitudinal magnetisation (Mz). The degree of recovery depends on the T1 relaxation time of each tissue, thereby generating image contrast."
Expected headings
"Physics"
"Key points"
"Potential pitfalls"