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Lint: antenatal-features-of-down-syndrome-1

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"Soft markers are sonographic findings that do not, in themselves, cause any adverse outcomes. However, they are seen more frequently in fetuses with an abnormality. This article addresses the soft markers that are specific to Down syndrome. For a general discussion, please refer to the article on soft markers."

Line 44:166 · 'y. T' should have one space.
Acronyms
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"PAPP-A"

Line 19:7 · 'PAPP-A' has no definition. Spell it out if it's unfamiliar to the audience.

"AFP: lower than in chromosomally normal fetuses"

Line 32:8 · 'AFP' has no definition. Spell it out if it's unfamiliar to the audience.
Strong
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"Soft markers"

Line 43:4 · Generally, don't use bold in text: '<strong>Soft markers</strong>'

"Structural abnormalities"

Line 122:4 · Generally, don't use bold in text: '<strong>Structural abnormalities</strong>'

"Adjunct features"

Line 163:4 · Generally, don't use bold in text: '<strong>Adjunct features</strong>'
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Maternal age"

Line 3:1 · "Maternal age" is not a recognised heading for this article type.

"Maternal serum screening"

Line 5:1 · "Maternal serum screening" is not a recognised heading for this article type.

"First trimester"

Line 7:1 · "First trimester" is not a recognised heading for this article type.

"Markers"

Line 9:1 · "Markers" should be H2, not H3.

"Second trimester"

Line 26:1 · "Second trimester" is not a recognised heading for this article type.

"Markers"

Line 28:1 · "Markers" should be H2, not H3.

"First trimester"

Line 37:1 · "First trimester" is not a recognised heading for this article type.

"Second trimester"

Line 41:1 · "Second trimester" is not a recognised heading for this article type.
There Is
suggestion

"There is a strong association between the incidence of Down syndrome and maternal age. Background risk based on maternal age is incorporated into both the serum screening-based risk calculations and the calculation of increased risk in the presence of a soft marker in the 2nd trimester (see below)."

Line 4:4 · Don't start a sentence with 'There is'.

"There is evidence that the inclusion of nasal bone measurement improves the specificity of 1st trimester data 5."

Line 39:4 · Don't start a sentence with 'There is'.