Radiopaedia Helpers

amyloid-related-imaging-abnormalities-aria

List Punctuation

error

"concurrent use of antithrombotic agents ^3,5."

Line 35:53 · Do not put full stops at the end of a list item.

Acronyms

warning

"Amyloid related imaging abnormalities (ARIA) represent a variety of imaging features identified in patients with Alzheimer disease being treated with novel amyloid lowering (anti-amyloid) therapies such as the monoclonal antibodies lecanemab, donanemab, and aducanumab (discontinued in 2024 after initial FDA approval) ^1-4."

Line 1:333 · 'FDA' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-E: 13%"

Line 8:8 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-H: 17%"

Line 9:8 · 'ARIA-H' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-E: 24%"

Line 15:8 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-H: 31%"

Line 16:8 · 'ARIA-H' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-E: 35%"

Line 22:8 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-H: 20%"

Line 23:8 · 'ARIA-H' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-E"

Line 41:5 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-E (E for oedema) is characterised by the presence of ¹:"

Line 42:4 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"parenchymal oedema (ARIA-E oedema)"

Line 45:24 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"sulcal effusions (ARIA-E effusions)"

Line 53:22 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"Although ARIA-E can occur bilaterally, it is most frequently (~two-thirds) unilateral ¹."

Line 57:13 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-H"

Line 58:5 · 'ARIA-H' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-H (H for haemorrhage) is usually seen in combination with ARIA-E and is characterised by the presence of ^1,4:"

Line 59:4 · 'ARIA-H' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-H (H for haemorrhage) is usually seen in combination with ARIA-E and is characterised by the presence of ^1,4:"

Line 59:67 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"Notably, anti-amyloid drugs were FDA approved using T2* for monitoring, instead of more sensitive sequences such as SWI ¹⁰."

Line 64:37 · 'FDA' has no definition. Spell it out if it's unfamiliar to the audience.

"Grading of ARIA-E and ARIA-H can be performed in a reproducible and standardised way, to allow safe continuation or reasonable discontinuation of therapy with an amyloid-lowering therapy ¹¹."

Line 66:15 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"Grading of ARIA-E and ARIA-H can be performed in a reproducible and standardised way, to allow safe continuation or reasonable discontinuation of therapy with an amyloid-lowering therapy ¹¹."

Line 66:26 · 'ARIA-H' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-E"

Line 67:5 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-H - microbleed subtype"

Line 73:5 · 'ARIA-H' has no definition. Spell it out if it's unfamiliar to the audience.

"ARIA-H - cortical superficial siderosis subtype"

Line 79:5 · 'ARIA-H' has no definition. Spell it out if it's unfamiliar to the audience.

"Both parenchymal oedema and sulcal effusions forms of ARIA-E are usually transient resolving over a number of months ¹. Blood products, in contrast, usually do not."

Line 87:58 · 'ARIA-E' has no definition. Spell it out if it's unfamiliar to the audience.

Emphasis

warning

"the number of APOE ε4 alleles (also known to correlate with increased risk of cerebral amyloid angiopathy)"

Line 34:22 · Italics should be used only in exceptional circumstances: '<em>APOE</em>'

Headings Case

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"ARIA-E"

Line 41:5 · 'ARIA-E' should use sentence-style capitalization.

"ARIA-H"

Line 58:5 · 'ARIA-H' should use sentence-style capitalization.

"ARIA-E"

Line 67:5 · 'ARIA-E' should use sentence-style capitalization.

"ARIA-H - microbleed subtype"

Line 73:5 · 'ARIA-H - microbleed subtype' should use sentence-style capitalization.

Headings Valid

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Expected headings

H1 Terminology
H1 Usage
H1 Epidemiology
H2 Risk factors
H2 Associations
H1 Clinical presentation
H2 Complications
H1 Diagnosis
H2 Diagnostic criteria
H2 Diagnostic clues
H1 Pathology
H2 Aetiology
H2 Location
H2 Classification
H2 Macroscopic appearance
H2 Microscopic appearance
H2 Immunophenotype
H2 Markers
H2 Genetics
H1 Radiographic features
H2 Plain radiograph
H2 Mammography
H2 Antenatal ultrasound
H2 Transoesophageal echocardiography
H2 Ultrasound
H2 CT
H3 Dual-energy CT
H2 Angiography (DSA)
H2 MRI
H2 CT/MRI
H2 Nuclear medicine
H3 PET-CT
H3 PET-MRI
H1 Radiology report
H1 Treatment and prognosis
H2 Complications
H1 History and etymology
H1 Differential diagnosis
H2 Clinical differential diagnosis
H1 Practical points
H1 See also

"ARIA-E"

Line 41:1 · "ARIA-E" is not a recognised heading for this article type.

"ARIA-H"

Line 58:1 · "ARIA-H" is not a recognised heading for this article type.

"Staging"

Line 65:1 · "Staging" is not a recognised heading for this article type.

"ARIA-E"

Line 67:1 · "ARIA-E" is not a recognised heading for this article type.

"ARIA-H - microbleed subtype"

Line 73:1 · "ARIA-H - microbleed subtype" is not a recognised heading for this article type.

"ARIA-H - cortical superficial siderosis subtype"

Line 79:1 · "ARIA-H - cortical superficial siderosis subtype" is not a recognised heading for this article type.

Commas

suggestion

"In most instances, ARIA is detected incidentally on imaging. Some patients describe various symptoms related, presumably, to cerebral oedema and irritation including headaches, vomiting, confusion, focal neurological deficits, and gait disturbance ⁴."

Line 28:112 · More than 5 commas in a single sentence might make it more difficult to read.

Semicolons

suggestion

"moderate: FLAIR hyperintensity of 5-10 cm extension or more than 1 FLAIR hyperintensity overall; generally"

Line 70:103 · Use semicolons judiciously.

"the imaging features of ARIA are essentially identical, with the only real distinguishing feature being clinical context; namely, ARIA occurs in individuals being treated with amyloid lowering agents"

Line 92:132 · Use semicolons judiciously.

Oxford Comma

suggestion

"severe: FLAIR hyperintensity extending >10 cm, solitary or multifocal"

Line 71:51 · Use the Oxford comma in 'cm, solitary or multifocal'.

Inline EG

suggestion

"perilesional oedema (e.g. around metastasis, primary tumour, abscess)"

Line 118:24 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.

Links

alzheimer-disease-1