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Lint: posterior-reversible-encephalopathy-syndrome-1

Strong
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"Posterior reversible encephalopathy syndrome also encompasses hypertensive brainstem encephalopathy (HBE), which is best described as an aetiology of posterior reversible encephalopathy syndrome with central features, so-called central posterior reversible encephalopathy syndrome (central PRES)."

Line 9:66 · Generally, don't use bold in text: '<strong>hypertensive brainstem encephalopathy (HBE)</strong>'

"Posterior reversible encephalopathy syndrome also encompasses hypertensive brainstem encephalopathy (HBE), which is best described as an aetiology of posterior reversible encephalopathy syndrome with central features, so-called central posterior reversible encephalopathy syndrome (central PRES)."

Line 9:249 · Generally, don't use bold in text: '<strong>central posterior reversible encephalopathy syndrome (central PRES)</strong>'

"DWI: usually normal, sometimes hyperintense due to oedema (T2 shine-through) or true restricted diffusion"

Line 89:29 · Generally, don't use bold in text: '<strong> </strong>usually normal, sometimes hyperintense due to oedema'
Acronyms
warning

"spinal cord involvement ("PRES-SCI")"

Line 70:34 · 'PRES-SCI' has no definition. Spell it out if it's unfamiliar to the audience.

"SMART syndrome"

Line 128:11 · 'SMART' has no definition. Spell it out if it's unfamiliar to the audience.
Commas
suggestion

"However, the presentation can be quite varied, and may include other neurological symptoms such as ataxia, focal neurological deficits, vertigo, nausea/vomiting, or tinnitus 19. Additionally, if patients have posterior reversible encephalopathy syndrome due to marked hypertension, there may be other clinical sequelae of hypertension present (e.g. renal impairment)."

Line 21:11 · More than 5 commas in a single sentence might make it more difficult to read.

"drug toxicity: e.g. tacrolimus, ciclosporin, bevacizumab, methotrexate, vincristine, cisplatin, cyclophosphamide, corticosteroids, rituximab, fluorouracil, cytarabine, bortezomib, azathioprine, L-asparaginase, ustekinumab, etc. 10,15,17,18,31"

Line 43:38 · More than 5 commas in a single sentence might make it more difficult to read.

"Typical posterior reversible encephalopathy syndrome manifests as bilateral vasogenic oedema within the occipital and parietal regions (70-90% of cases), perhaps relating to the posterior cerebral artery supply. Despite its name, however, posterior reversible encephalopathy syndrome can be found in a non-posterior distribution, mainly in watershed areas, including within the frontal, inferior temporal, cerebellar, and brainstem regions 2,19. Both cortical and subcortical locations are affected."

Line 62:239 · More than 5 commas in a single sentence might make it more difficult to read.
Inline EG
suggestion

"However, the presentation can be quite varied, and may include other neurological symptoms such as ataxia, focal neurological deficits, vertigo, nausea/vomiting, or tinnitus 19. Additionally, if patients have posterior reversible encephalopathy syndrome due to marked hypertension, there may be other clinical sequelae of hypertension present (e.g. renal impairment)."

Line 21:358 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.
Semicolons
suggestion

"acute infarct demonstrates restricted diffusion; posterior reversible encephalopathy syndrome with vasogenic oedema alone does not restrict"

Line 118:55 · Use semicolons judiciously.