"Central nervous system (CNS) chagoma, or brain chagoma describes CNS involvement from Chagas disease, a parasitic disease caused by the protozoan Trypanosoma cruzi 8."
"Brain chagoma is distinct from the cutaneous lesion chagoma, which can occur at the site of the causative Trypanosoma cruzi inoculation."
"Trypanosoma cruzi is a flagellated protozoan that has a complex life cycle involving mammalian hosts and Triatominae vectors. Once penetrated into host cells, Trypanosoma cruzi have clever ways of invading host immunity and establishing persistance in infected tissue and bloodstream 8."
"Chagas disease was described in 1909 by the Brazilian Carlos Justiniano Ribeiro Chagas (1879-1934), head of the Oswaldo Cruz Institute and director of the Malaria Control Program 3. He named Trypanosoma cruzi after his mentor, Oswaldo Cruz, with whom he studied what we now know as Chagas disease, infecting various mammals and studying the parasite that developed in their blood 3."
"Symptoms are consistent to those with space occupying lesions or acute diffuse meningoencephalitis, i.e. headache, focal neurological deficits, fever, meningism, seizures and altered conscious state 7."