"Typically, patients have a large deletion in mitochondrial DNA (mtDNA) (e.g. Kearns-Sayre syndrome, Pearson syndrome, MNGIE), but autosomal dominant or recessive forms due to mutations in nuclear genes that affect mitochondrial DNA (mtDNA) repair or replication have also been reported (e.g. POLG-related disorders, TWNK) 1,4. It is sporadic in a majority of cases 4."
"Lambert-Eaton myasthenic syndrome"
"Typically, patients have a large deletion in mitochondrial DNA (mtDNA) (e.g. Kearns-Sayre syndrome, Pearson syndrome, MNGIE), but autosomal dominant or recessive forms due to mutations in nuclear genes that affect mitochondrial DNA (mtDNA) repair or replication have also been reported (e.g. POLG-related disorders, TWNK) 1,4. It is sporadic in a majority of cases 4."
"Typically, patients have a large deletion in mitochondrial DNA (mtDNA) (e.g. Kearns-Sayre syndrome, Pearson syndrome, MNGIE), but autosomal dominant or recessive forms due to mutations in nuclear genes that affect mitochondrial DNA (mtDNA) repair or replication have also been reported (e.g. POLG-related disorders, TWNK) 1,4. It is sporadic in a majority of cases 4."