"Dual-energy CT, with iodine maps and virtual non-contrast reconstructions, is able to differentiate contrast staining in contrast-induced neurotoxicity from haemorrhage, as has been demonstrated in post-endovascular reperfusion contrast staining 3,4."
"Although contrast-induced neurotoxicity is rare and sporadic, patients with end-stage renal failure, hypertension, diabetes mellitus and those receiving higher doses of intra-arterial injection directly into the aortic arch (e.g. coronary angiography), proximal vessels (e.g. internal mammary coronary grafts) or cranial vessels (e.g. cerebral angiography) are at higher risk 1,4,5. The most commonly implicated contrast products are iodixanol, iopamidol, and iohexol 5. There is no sex predilection 5."
"Patients typically report rapidly evolving neurological deficits shortly after the procedure (1-12 hours), which vary according to the part of the brain affected 5. More common reported signs and symptoms include headache, seizures, encephalopathy, and focal neurological deficits such as cortical blindness, hemiparesis and aphasia 1,2,5."
"Although contrast-induced neurotoxicity is rare and sporadic, patients with end-stage renal failure, hypertension, diabetes mellitus and those receiving higher doses of intra-arterial injection directly into the aortic arch (e.g. coronary angiography), proximal vessels (e.g. internal mammary coronary grafts) or cranial vessels (e.g. cerebral angiography) are at higher risk 1,4,5. The most commonly implicated contrast products are iodixanol, iopamidol, and iohexol 5. There is no sex predilection 5."
"There is no global consensus diagnostic criteria. An Australian diagnostic criteria proposes the following to attain either a 'probable' or 'possible' diagnosis of contrast-induced neurotoxicity 8:"
"Patients typically report rapidly evolving neurological deficits shortly after the procedure (1-12 hours), which vary according to the part of the brain affected 5. More common reported signs and symptoms include headache, seizures, encephalopathy, and focal neurological deficits such as cortical blindness, hemiparesis and aphasia 1,2,5."