"Hepatic adenomas are usually solitary (70-80% of cases 10) and large at the time of diagnosis (5-15 cm) 3,13. They are most frequently seen at a subcapsular location in the right lobe of the liver and are often round, well-defined, pseudo-encapsulated masses. Occasional dystrophic calcification may be present."
"hypoechoic: 20-40%, particularly if there is hepatic steatosis. A hypoechoic halo of focal fatty sparing is also frequently seen."
">80% of beta-catenin mutated exon 3 HCA are iso or hyperintense during the hepatobiliary phase due to increased OATP expression22. This imaging feature can be used in risk stratification."
"T1: variable and can range from being hyper-, iso-, to hypointense (hyperintense in 35-77% of cases 8)"
"T2: mildly hyperintense (in 47-74% of cases 2,8)"
"IP/OP: presence of fat typically leads to signal dropout on out-of-phase imaging"
"T1 C+ (Eovist/Primovist): "
">80% of beta-catenin mutated exon 3 HCA are iso or hyperintense during the hepatobiliary phase due to increased OATP expression22. This imaging feature can be used in risk stratification."
"highest risk of HCC transformation 21"
"negligible risk of HCC transformation"
"IP/OP: presence of fat typically leads to signal dropout on out-of-phase imaging"
">80% of beta-catenin mutated exon 3 HCA are iso or hyperintense during the hepatobiliary phase due to increased OATP expression22. This imaging feature can be used in risk stratification."
">80% of beta-catenin mutated exon 3 HCA are iso or hyperintense during the hepatobiliary phase due to increased OATP expression22. This imaging feature can be used in risk stratification."
"In inoperable cases, hepatic arterial embolisation may have a role 7. Embolisation is the treatment of choice for an acutely bleeding HCA."
"Sonic hedgehog-activated hepatic adenoma"
"T2: bright central scar that has late enhancement"
Expected headings
"Molecular classifications"
"Complications"
"Hepatic adenomas, or hepatocellular adenomas, are benign, generally hormone-induced liver tumours with a predilection for haemorrhage. They need to be differentiated from other focal liver tumours (especially focal nodular hyperplasia and hepatocellular carcinoma). Although usually solitary, hepatic adenomas can be multiple and numerous in a number of conditions; when more than 10 in number, the term hepatic adenomatosis should be used 23. This is discussed separately."
"hypervascular; similar to focal nodular hyperplasia (FNH), although adenomas usually enhance to a lesser degree"
"diffuse or centripetal (periphery-to-centre) filling; the latter is helpful, as FNH shows centrifugal filling 11,16,23"
"Larger lesions (>5 cm) often demonstrate more heterogeneous features, including fibrosis, haemorrhage, necrosis and calcification 23."
"Management is usually determined by a number of factors, including patient sex, tumour size, location and the presence of any complications 23."