"Treatment and prognosis "
"glucose-6-phosphate dehydrogenase (G6PD) deficiency"
Expected headings
"Radiological features"
"Treatment and prognosis "
"Patients with hyperuricaemia may be asymptomatic or have symptoms and signs relating to one of the complications of hyperuricaemia (e.g. gout, nephrolithiasis)."
"drugs (e.g. diuretics)"
"haematological diseases (e.g. haemolytic anaemia, lymphoma, leukaemia)"
"No radiological features are specific for hyperuricaemia. Signs of complications of hyperuricaemia may be visible (e.g. gout, nephrolithiasis)."
"Uric acid is produced as the end product of purine nucleotide degradation. Hypoxanthine and xanthine are the intermediates which are converted to uric acid via the enzyme xanthine oxidase. Uric acid is mostly excreted via the kidneys, the remainder being excreted intestinally, but up to 90% is resorbed via the transporters URAT1 and GLUT9 in the kidneys 1,2. Hyperuricaemia may result from urate underexcretion, overproduction or a combination of both."